DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub56D and TUB5

DIOPT Version :9

Sequence 1:	NP_725896.1	Gene:	betaTub56D / 37238	FlyBaseID:	FBgn0284243	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_564101.1	Gene:	TUB5 / 838590	AraportID:	AT1G20010	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	427	Identity:	362/427 - (84%)
Similarity:	403/427 - (94%)	Gaps:	1/427 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FWEIISDEHGIDATGAYHGD-SDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQ 92
            |||:|.||||||:||.|.|| :|||||||||||||||||:|||||||:|||||||||:|||||||
plant    20 FWEVICDEHGIDSTGRYSGDTADLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSIRSGPFGQ 84

  Fly    93 IFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMG 157
            |||||||||||||||||||||||||||||:|:||||||||||:||||||||:.||||||||||||
plant    85 IFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMG 149

  Fly   158 TLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR 222
            ||||||||||||||:|.|:||.|||||||||||||||||||||||||.||...:|||||||||||
plant   150 TLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFR 214

  Fly   223 TLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 287
            ||||:||::||||||:|.||||||..||||||||:||||||||::|||||||||.||||||||||
plant   215 TLKLSTPSFGDLNHLISATMSGVTCSLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGS 279

  Fly   288 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVE 352
            |||.:||||||||||:|:||||.|.|||||||||.:|||||:||.||||||:|||||||||||||
plant   280 QQYISLTVPELTQQMWDSKNMMCAADPRHGRYLTASAIFRGQMSTKEVDEQILNIQNKNSSYFVE 344

  Fly   353 WIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF 417
            |||||||::||||||:||||:|||:||||:|||:|:|:|||||||||||||||||||||||||||
plant   345 WIPNNVKSSVCDIPPKGLKMAATFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEF 409

  Fly   418 TEAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEVD 454
            |||||||||||:||||||:|||||:.|::.|:|.|.|
plant   410 TEAESNMNDLVAEYQQYQDATADEEGEYDVEEEEEGD 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	350/406 (86%)
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	352/409 (86%)
TUB5	NP_564101.1	PLN00220	1..431	CDD:215107	353/410 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68504
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840