DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTub56D and TUB4

DIOPT Version :9

Sequence 1:	NP_725896.1	Gene:	betaTub56D / 37238	FlyBaseID:	FBgn0284243	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_199247.1	Gene:	TUB4 / 834459	AraportID:	AT5G44340	Length:	444	Species:	Arabidopsis thaliana

Alignment Length:	422	Identity:	359/422 - (85%)
Similarity:	396/422 - (93%)	Gaps:	1/422 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 93
            |||:|.||||||.||.|.|||.||||||:||:||||||||||||||:|||||||||:||||||||
plant    20 FWEVICDEHGIDHTGQYVGDSPLQLERIDVYFNEASGGKYVPRAVLMDLEPGTMDSLRSGPFGQI 84

  Fly    94 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 158
            ||||||||||||||||||||||||||||:||||||||||||:.|||||||:.|||||||||||||
plant    85 FRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENSDCLQGFQVCHSLGGGTGSGMGT 149

  Fly   159 LLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 223
            |||||||||||||:|.|:||.|||||||||||||||||||||||||.||...:||||||||||||
plant   150 LLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRT 214

  Fly   224 LKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 288
            |||..||:||||||:|.||||||.|||||||||:||||||||::|||||||||.|||||||||||
plant   215 LKLANPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQ 279

  Fly   289 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEW 353
            ||.||:||||||||:||||||.|.|||||||||.:|:|||::|.|||||||:|||||||||||||
plant   280 QYSALSVPELTQQMWDAKNMMCAADPRHGRYLTASAVFRGKLSTKEVDEQMMNIQNKNSSYFVEW 344

  Fly   354 IPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 418
            ||||||::||||.|:||||::|||||||:|||:|:|:||||||||||||||||||||||||||||
plant   345 IPNNVKSSVCDIAPKGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFT 409

  Fly   419 EAESNMNDLVSEYQQYQEATADEDAEFEEEQE 450
            ||||||||||:||||||:|||.|: |:|||:|
plant   410 EAESNMNDLVAEYQQYQDATAGEE-EYEEEEE 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	348/405 (86%)
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	350/408 (86%)
TUB4	NP_199247.1	PLN00220	1..431	CDD:215107	352/410 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840