Protein Alignment betaTub56D and TUBG1

DIOPT Version :10

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_001061.2
• Gene: TUBG1 / 7283
• HGNCID: 12417
• Length: 451
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 141/420 - (33%)
• Similarity: 241/420 - (57%)
• Gaps: 22/420 - (5%)

  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 93
            ||:.:..||||...|.....:....:|.:|::.:|....|:|||||:||||..:.|:.:.|:.::
Human    21 FWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKL 85

  Fly    94 FRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGM 156
            :.|:|....:  .|||||||.| :::|.::.:.:.|::.:||:..|.|:||.|.||:.||||||:
Human    86 YNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGL 149

  Fly   157 GTLLISKIREEYPDRIMNTYSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDIC 220
            |:.|:.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|.:|.|....:||.||..|.
Human   150 GSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 214

  Fly   221 FRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 285
            ...|.:..|::..:|.|||..||..||.||:||.:|.||..|..:::|.|||||.|.|:.|||:.
Human   215 TDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD 279

  Fly   286 GS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR-------YLTVAAIFRGRMSMKEVDEQMLNI 342
            .| ...|..||.::.:::...||:|.:.    ||       |:.:..|.:|.:...:|.:.:..|
Human   280 QSVASVRKTTVLDVMRRLLQPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRI 340

  Fly   343 QNKNSSYFVEWIPNNVKTAV---CDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFL 404
            :.:..:.|:.|.|.:::.|:   ....|...::|...:.|.|:|..||:|...|:..:.:|:|||
Human   341 RERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFL 405

  Fly   405 HWYTGEGMDEMEFTEAESN---MNDLVSEY 431
            ..:..|.|.:..|.|.:::   :..|:.||
Human   406 EQFRKEDMFKDNFDEMDTSREIVQQLIDEY 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	141/420 (34%)
TUBG1	NP_001061.2	gamma_tubulin	3..435	CDD:276957	139/418 (33%)