Protein Alignment betaTub56D and TUBE1

DIOPT Version :9

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_057346.1
• Gene: TUBE1 / 51175
• HGNCID: 20775
• Length: 475
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 146/449 - (32%)
• Similarity: 231/449 - (51%)
• Gaps: 54/449 - (12%)

  Fly    28 CFWEIISDEH-GIDATGAYHGDSDLQLERINVYYNEA-----------SGGKYV---PRAVLVDL 77
            |||::...|| .::..|.|.       |.|:.::...           |.||..   .||||:|:
Human    19 CFWDLALREHAAVNQKGIYD-------EAISSFFRNVDTRVVGDGGSISKGKICSLKARAVLIDM 76

  Fly    78 EPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGF 142
            |.|.::.:..||...:|.....:...||:|||||.||...|:...|.:|:..||.||.|||||.|
Human    77 EEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLYQDQILEKFRKSAEHCDCLQCF 141

  Fly   143 QLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDE 207
            .:.||:|||||||:||.|:..:.:|:|:......|:.||.: .|.:..|||:.|::.:|.|:.|.
Human   142 FIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGE-DDVITSPYNSILAMKELNEHADC 205

  Fly   208 TYCIDNEALYDICFR------------TLK---LTTPTYGDL-----------NHLVSLTMSGVT 246
            ...|||::|:||..:            |:|   |.|.:.|.|           |::|:..:..:|
Human   206 VLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLT 270

  Fly   247 TCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAA 311
            :..||.|.||.||.::::|:||||:||:.:....||.:..........:.::....|...:.:..
Human   271 SSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLR 335

  Fly   312 CDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQN-KNSSYFVEWIPNNVKTAVCDIPPRGLKMSAT 375
            .||:|..||..|.:.||.:   ::.:...||:. |.|..||.|.....||::|.:||.|...|..
Human   336 ADPKHSLYLACALMVRGNV---QISDLRRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLL 397

  Fly   376 FIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG-EGMDEMEFTEAESNMNDLVSEYQQ 433
            .:.|:|.::..|..:.|:|..::::||.||.|.. |||:|..||||.|:::.|:.||.|
Human   398 ALANNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	146/449 (33%)
		PLN00220	29..438	CDD:215107	145/448 (32%)
TUBE1	NP_057346.1	epsilon_tubulin	2..457	CDD:276959	146/449 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810