Protein Alignment betaTub56D and TUBD1

DIOPT Version :10

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_057345.2
• Gene: TUBD1 / 51174
• HGNCID: 16811
• Length: 453
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 106/456 - (23%)
• Similarity: 194/456 - (42%)
• Gaps: 78/456 - (17%)

  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSV--RSGPFG 91
            |..::||.|......:...:...|......:::|...|..:.||||||:||..::.:  ::...|
Human    20 FDALLSDSHSSQGLCSMRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQMLSKAAQSG 84

  Fly    92 QIFRPDNFVFGQ-------SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLG 149
            |      :.:||       .|:|||||.|:...|....:|:::::|||.|.||...||.:..|:.
Human    85 Q------WKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMNIIRKEVEKCDSFSGFFIIMSMA 143

  Fly   150 GGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNE 214
            ||||||:|..:...:.::|.:.:.....:.|. ...:.:|:.||:.|::..|..::|.....:|:
Human   144 GGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPY-GTGEVIVQNYNSILTLSHLYRSSDALLLHEND 207

  Fly   215 ALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNAD---------LRKLAVNMVPFP 270
            |::.||.:.:.:...::.|:|.:::..:..|     |....:|:         |..|..::||.|
Human   208 AIHKICAKLMNIKQISFSDINQVLAHQLGSV-----FQPTYSAESSFHYRRNPLGDLMEHLVPHP 267

  Fly   271 RLHFFMPGFAPLTSRGSQQYRALT----VPELTQQMFDAKNMMAACDPRH--------------- 316
            ..........|..|..|..|...|    :..|.|.:.....|....| ||
Human   268 EFKMLSVRNIPHMSENSLAYTTFTWAGLLKHLRQMLISNAKMEEGID-RHVWPPLSGLPPLSKMS 331

  Fly   317 -------GRYLTVAAIFRGRMSMKEVDEQMLNIQN-KNSSYFVEWI-PNNV----KTAVCDIPPR 368
                   ...:....|.||:      |.|..:::. |:.:.:..|: |.|.    ||      .|
Human   332 LNKDLHFNTSIANLVILRGK------DVQSADVEGFKDPALYTSWLKPVNAFNVWKT------QR 384

  Fly   369 GL---KMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSE 430
            ..   :.||..:.||..:.:....|..:...||..||::|.||..|::|.:|.::.:::..:|:.
Human   385 AFSKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVAS 449

  Fly   431 Y 431
            |
Human   450 Y 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	106/456 (23%)
TUBD1	NP_057345.2	delta_zeta_tubulin-like	2..452	CDD:276958	106/456 (23%)