Protein Alignment betaTub56D and TUBB8B

DIOPT Version :9

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_001345618.1
• Gene: TUBB8B / 260334
• HGNCID: 24983
• Length: 444
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 372/425 - (87%)
• Similarity: 398/425 - (93%)
• Gaps: 2/425 - (0%)

  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 93
            |||:|||||.||:.|.|||||.||||||||:::|||||:||||||||||||||||||.||||||:
Human    20 FWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYVPRAVLVDLEPGTMDSVHSGPFGQV 84

  Fly    94 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 158
            ||||||:.||.|||||||||.|||||||.:||:||||||||||||||||||||||||||||||||
Human    85 FRPDNFISGQCGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 149

  Fly   159 LLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 223
            ||||||||||||||:||:|::||||||||||||||||||||||:||.|||:|||||||||||.||
Human   150 LLISKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSRT 214

  Fly   224 LKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 288
            |||.||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
Human   215 LKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 279

  Fly   289 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEW 353
            |||||||.|||||||||||||||||||||.||||||||||||.|:||||||.|||:||||||.:|
Human   280 QYRALTVAELTQQMFDAKNMMAACDPRHGCYLTVAAIFRGRMPMREVDEQMFNIQDKNSSYFADW 344

  Fly   354 IPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 418
            .|:|||||||||||||||||||||||:.||||||..:||||||||||||||||||||||||||||
Human   345 FPDNVKTAVCDIPPRGLKMSATFIGNNAAIQELFTCVSEQFTAMFRRKAFLHWYTGEGMDEMEFT 409

  Fly   419 EAESNMNDLVSEYQQYQEATA--DEDAEFEEEQEA 451
            |||||||||||||||||:|||  :||.|:.||:.|
Human   410 EAESNMNDLVSEYQQYQDATAEEEEDEEYAEEEVA 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	361/405 (89%)
		PLN00220	29..438	CDD:215107	363/408 (89%)
TUBB8B	NP_001345618.1	PLN00220	1..427	CDD:215107	362/406 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	421..444		14/22 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930