DRSC/TRiP Functional Genomics Resources

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Protein Alignment betaTub56D and TUBB4B

DIOPT Version :10

Sequence 1:NP_725896.1 Gene:betaTub56D / 37238 FlyBaseID:FBgn0284243 Length:456 Species:Drosophila melanogaster
Sequence 2:NP_006079.1 Gene:TUBB4B / 10383 HGNCID:20771 Length:445 Species:Homo sapiens


Alignment Length:425 Identity:411/425 - (96%)
Similarity:419/425 - (98%) Gaps:0/425 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 93
            |||:||||||||.||.|||||||||||||||||||:|||||||||||||||||||||||||||||
Human    20 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 84

  Fly    94 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 158
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    85 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 149

  Fly   159 LLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 223
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||
Human   150 LLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 214

  Fly   224 LKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 288
            ||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
Human   215 LKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 279

  Fly   289 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEW 353
            ||||||||||||||||||||||||||||||||||||:||||||||||||||||:|||||||||||
Human   280 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEW 344

  Fly   354 IPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 418
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   345 IPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 409

  Fly   419 EAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEV 453
            |||||||||||||||||:|||:|:.|||||.|.||
Human   410 EAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEV 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
betaTub56DNP_725896.1 PLN00220 29..438 CDD:215107 399/408 (98%)
TUBB4BNP_006079.1 PLN00220 1..427 CDD:215107 398/406 (98%)
MREI motif. /evidence=ECO:0000250|UniProtKB:P07437 1..4
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 426..445 13/19 (68%)
Blue background indicates that the domain is not in the aligned region.

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