Protein Alignment betaTub56D and TUBB4A

DIOPT Version :10

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_001276052.1
• Gene: TUBB4A / 10382
• HGNCID: 20774
• Length: 495
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 405/425 - (95%)
• Similarity: 417/425 - (98%)
• Gaps: 1/425 - (0%)

  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 93
            |||:||||||||.||.|||||||||||||||||||:||.||||||||||||||||||||||||||
Human    71 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQI 135

  Fly    94 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 158
            ||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||
Human   136 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 200

  Fly   159 LLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 223
            |||||||||:|||||||:|||||||||||||||||||||||||||||||||||||||||||||||
Human   201 LLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 265

  Fly   224 LKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 288
            ||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
Human   266 LKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 330

  Fly   289 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEW 353
            ||||||||||||||||||||||||||||||||||||:|||||||||||||||::|:|||||||||
Human   331 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEW 395

  Fly   354 IPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 418
            |||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||
Human   396 IPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 460

  Fly   419 EAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEV 453
            |||||||||||||||||:||| |:.|||||.|.||
Human   461 EAESNMNDLVSEYQQYQDATA-EEGEFEEEAEEEV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	393/408 (96%)
TUBB4A	NP_001276052.1	PLN00220	52..478	CDD:215107	392/406 (97%)