DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl6 and ARL14

DIOPT Version :9

Sequence 1:	NP_611421.1	Gene:	Arl6 / 37236	FlyBaseID:	FBgn0034446	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_079323.1	Gene:	ARL14 / 80117	HGNCID:	22974	Length:	192	Species:	Homo sapiens

Alignment Length:	161	Identity:	48/161 - (29%)
Similarity:	96/161 - (59%)	Gaps:	6/161 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ILVLGLNNSGKSSIINHFKKSSEQTSIVVPTVGFMVEQFYIGMSGVSIKAIDMSGATRYRNLWEH 84
            :|:|||:::|||:::...|.:.:.|:|  ||:||.||...:..: :|:...|:.|..:.|.:|..
Human    16 VLLLGLDSAGKSTLLYKLKLAKDITTI--PTIGFNVEMIELERN-LSLTVWDVGGQEKMRTVWGC 77

  Fly    85 QFKNCHGIIYVIDSSDRMRFVVVKDELDLVLQHPDLCNRIVPILFYGNKMDMEDSLSSVKIAAAL 149
            ..:|..|::||:||:|:.|....:.:.:.:|::..:.|  ||::...||.||..:|::..|....
Human    78 YCENTDGLVYVVDSTDKQRLEESQRQFEHILKNEHIKN--VPVVLLANKQDMPGALTAEDITRMF 140

  Fly   150 RLENI-KDKPWHICSSSAISGEGLGEGVQWL 179
            :::.: .|:.|::....|::||||.:|.:.|
Human   141 KVKKLCSDRNWYVQPCCALTGEGLAQGFRKL 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6	NP_611421.1	Arl6	19..182	CDD:206722	48/161 (30%)
ARL14	NP_079323.1	SAR	1..175	CDD:197556	48/161 (30%)
ARL14	NP_079323.1	ARLTS1	15..174	CDD:133356	48/161 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271528at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820