DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl6 and arl6

DIOPT Version :9

Sequence 1:	NP_611421.1	Gene:	Arl6 / 37236	FlyBaseID:	FBgn0034446	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	XP_021329928.1	Gene:	arl6 / 494134	ZFINID:	ZDB-GENE-041219-2	Length:	194	Species:	Danio rerio

Alignment Length:	196	Identity:	100/196 - (51%)
Similarity:	139/196 - (70%)	Gaps:	2/196 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGMLHNLADLIKIKKDKMTILVLGLNNSGKSSIINHFKKSSEQTSIVVPTVGFMVEQFYIGMSGV 65
            ||:...||..:.:||.::.:|.|||:||||::|||..|.|:.|...:|||:||.:|:|  ..|.:
Zfish     1 MGLFDKLAGWLGLKKKEVNVLCLGLDNSGKTTIINQLKPSNAQAQDIVPTIGFSIEKF--KTSSL 63

  Fly    66 SIKAIDMSGATRYRNLWEHQFKNCHGIIYVIDSSDRMRFVVVKDELDLVLQHPDLCNRIVPILFY 130
            |....||||..||||||||.:|....||:||||.|::|.||.|:|||.:|.|||:.:|.:|:||:
Zfish    64 SFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSGDKLRMVVAKEELDTLLNHPDIKHRRIPLLFF 128

  Fly   131 GNKMDMEDSLSSVKIAAALRLENIKDKPWHICSSSAISGEGLGEGVQWLIQQMRFAMLNNKNAAK 195
            .||||:.|:||:||::..|.||||||||||||:|.|:.||||.|||.||.:|:..:..:::|...
Zfish   129 ANKMDLRDALSAVKVSQLLCLENIKDKPWHICASDAVKGEGLLEGVDWLQEQIALSNQSDENVKP 193

  Fly   196 S 196
            |
Zfish   194 S 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6	NP_611421.1	Arl6	19..182	CDD:206722	91/162 (56%)
arl6	XP_021329928.1	Arl6	19..180	CDD:206722	91/162 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592013
Domainoid	1	1.000	200	1.000	Domainoid score	I2992
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12960
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3660
OMA	1	1.010	-	-		QHG53833
OrthoDB	1	1.010	-	-		D1271528at2759
OrthoFinder	1	1.000	-	-		FOG0007847
OrthoInspector	1	1.000	-	-		oto38635
orthoMCL	1	0.900	-	-		OOG6_105712
Panther	1	1.100	-	-	LDO	PTHR11711
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2408
SonicParanoid	1	1.000	-	-		X5803
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800