DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arl6 and arl-6

DIOPT Version :9

Sequence 1:	NP_611421.1	Gene:	Arl6 / 37236	FlyBaseID:	FBgn0034446	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_497993.1	Gene:	arl-6 / 183311	WormBaseID:	WBGene00000193	Length:	190	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	69/179 - (38%)
Similarity:	113/179 - (63%)	Gaps:	2/179 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGMLHNLADLIKIKKDKMTILVLGLNNSGKSSIINHFKKSSEQTSIVVPTVGFMVEQFYIGMSGV 65
            ||...:|:.|..:.|..:.|:|:||:||||::|:|..|....::..:|||||.:|..|  ....:
Worm     1 MGFFSSLSSLFGLGKKDVNIVVVGLDNSGKTTILNQLKTPETRSQQIVPTVGHVVTNF--STQNL 63

  Fly    66 SIKAIDMSGATRYRNLWEHQFKNCHGIIYVIDSSDRMRFVVVKDELDLVLQHPDLCNRIVPILFY 130
            |..|.||:|..:||:.||..|.:..|:|:|:|||||:|..::||||.:|::|.|:.:|.:||:..
Worm    64 SFHAFDMAGQMKYRSTWESYFHSSQGVIFVLDSSDRLRMELLKDELMMVMEHKDVVSRGIPIVIL 128

  Fly   131 GNKMDMEDSLSSVKIAAALRLENIKDKPWHICSSSAISGEGLGEGVQWL 179
            .||||:..::::..|..||.|...:...|.|.|:.|::|:||.:.:|.|
Worm   129 ANKMDIPGAMTASDITVALGLNLYRSGTWSIHSTCALTGDGLDKAMQQL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6	NP_611421.1	Arl6	19..182	CDD:206722	64/161 (40%)
arl-6	NP_497993.1	small_GTP	17..173	CDD:272973	62/157 (39%)
arl-6	NP_497993.1	Arl6	19..180	CDD:206722	64/161 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12960
Inparanoid	1	1.050	139	1.000	Inparanoid score	I3087
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53833
OrthoDB	1	1.010	-	-		D1271528at2759
OrthoFinder	1	1.000	-	-		FOG0007847
OrthoInspector	1	1.000	-	-		oto18357
orthoMCL	1	0.900	-	-		OOG6_105712
Panther	1	1.100	-	-	LDO	PTHR11711
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2408
SonicParanoid	1	1.000	-	-		X5803
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800