DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arl6 and arc-1

DIOPT Version :9

Sequence 1:	NP_611421.1	Gene:	Arl6 / 37236	FlyBaseID:	FBgn0034446	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_496089.3	Gene:	arc-1 / 174525	WormBaseID:	WBGene00000180	Length:	539	Species:	Caenorhabditis elegans

Alignment Length:	190	Identity:	53/190 - (27%)
Similarity:	88/190 - (46%)	Gaps:	35/190 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LHNLADLIKIKKDKMTILVLGLNNSGKSSIINHFKKSSEQTSIVV-PTVGFMVEQFYIGMSGVSI 67
            || :.|.|:.:     :::|||:.:||:||:...||....|.:.. ||:||.:|.  |......:
Worm   362 LH-IGDFIESR-----VVLLGLDGAGKTSIVRRLKKVQMDTVMAPHPTIGFNIET--IHYKNYRL 418

  Fly    68 KAIDMSGATRYRNLWEHQFKNCHGIIYVIDSSDRMRFVVVKDELDLVLQHP--DLCNRIVPILFY 130
            ...|:.|..:.|:||:|.:.|...|.||||.....||.....||:.|:..|  ..|    |::..
Worm   419 NFWDVGGLPKLRHLWKHYYSNAQAIFYVIDGYAVERFSEAIKELNRVMSDPLVGTC----PVIVA 479

  Fly   131 GNKMD-------MEDSLSSVKIAAALRLENIKDKPWHICSSSAISGEGLGEGVQWLIQQM 183
            .|:.|       |:..||.::   ||..::    .:|.|.::.      |.|:..:|.|:
Worm   480 VNRKDGYALNGHMDALLSQLE---ALPFQH----HFHCCDAAT------GSGIDQIIDQI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6	NP_611421.1	Arl6	19..182	CDD:206722	48/172 (28%)
arc-1	NP_496089.3	zf-RING_5	6..54	CDD:291308
		zf-B_box	105..149	CDD:279037
		Apolipoprotein	201..>306	CDD:279749
		BBC	208..339	CDD:128778
		Arf_Arl	371..526	CDD:206644	48/178 (27%)
		small_GTP	371..526	CDD:272973	48/178 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900