DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl6 and ARL9

DIOPT Version :9

Sequence 1:	NP_611421.1	Gene:	Arl6 / 37236	FlyBaseID:	FBgn0034446	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_001350723.1	Gene:	ARL9 / 132946	HGNCID:	23592	Length:	265	Species:	Homo sapiens

Alignment Length:	142	Identity:	41/142 - (28%)
Similarity:	73/142 - (51%)	Gaps:	8/142 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IKKDKMTILVLGLNNSGKSSIINHFKKSSEQTSIVVPTVGFMVEQFYIGMSGVSIKAIDMSGATR 77
            ::|:|. ||||||:.:||:|:::....:..|.| |.||.||  ....|......::.:::.|:..
Human    93 LEKNKQ-ILVLGLDGAGKTSVLHSLASNRVQHS-VAPTQGF--HAVCINTEDSQMEFLEIGGSKP 153

  Fly    78 YRNLWEHQFKNCHGIIYVIDSSDRMRFVVVKDELDLVLQHPDLCNRIVPILFYGNKMDMEDSLSS 142
            :|:.||........:|:|:||:|..|....|..|..::    ..|.::|::.:.||.|:|.:...
Human   154 FRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLI----AANPVLPLVVFANKQDLEAAYHI 214

  Fly   143 VKIAAALRLENI 154
            ..|..||.|..:
Human   215 TDIHEALALSEV 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6	NP_611421.1	Arl6	19..182	CDD:206722	39/136 (29%)
ARL9	NP_001350723.1	Arl9_Arfrp2_like	98..263	CDD:133362	39/137 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900