Protein Alignment Fak and Cad96Ca

DIOPT Version :10

• Sequence 1: NP_001137718.1
• Gene: Fak / 37233
• FlyBaseID: FBgn0020440
• Length: 1500
• Species: Drosophila melanogaster
• Sequence 2: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 133/499 - (26%)
• Similarity: 223/499 - (44%)
• Gaps: 114/499 - (22%)

  Fly   316 LPKEKLSKSG---ENTTEPELQNFNCNCQKIKTQIKI-SASNNVEDLVITCNGINTAESIADLID 376
            :|.|..:.||   .|::.|               |.| |..:....:|:|..|...|  ||.|:.
  Fly   287 IPAETTTPSGGHHNNSSSP---------------ITIFSLKSGTIPIVVTVGGFFVA--IAVLLA 334

  Fly   377 GYCR----LLSKDLEFTIWHRETNASNEDSAKALPNDATLGSNKSTSSQGKPMLTDDYA-EIGLL 436
            ..||    .:|:.|:.|       ...|:.||           ||..||....||||.. .:.:.
  Fly   335 YLCRRRLCAISRTLKKT-------KEKEELAK-----------KSNQSQLSSTLTDDSRNSMVMQ 381

  Fly   437 EGEGDYS-----TPTVRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGK---NL------ 487
            :.:|..:     .|..|:.::  .:.|.....||...|   |.:..:|..|.|:   ||
  Fly   382 QWQGPVAFANRYVPWERDQQM--GIATSQLSTGVTNGG---VSSPGVPSPGTGEPGSNLGPGCLT 441

  Fly   488 -----AGNGKNSNSDQRNAD--------------------------------SRPDVIQVAIKTC 515
                 :|..:|:.:.:.|.|                                ....:..||:||.
  Fly   442 GGAGSSGAPENAFAGEANCDRWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTL 506

  Fly   516 KANDDPEKTENFLAEAYIMQKFD-HPHIIRLIGICSVM-PIWIVMELAKLGELRAYLKTN-SER- 576
            |.:......::.|:|..:|:..: |.:::.|:|.|:.. |.::::|....|:|:.||::: :||
  Fly   507 KESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERH 571

  Fly   577 --LSHG--------TLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVS 631
              .:||        .|..:.||::..:.||.|:..:|||:||||:|::.....|:||||.:|.|.
  Fly   572 YGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVI 636

  Fly   632 DQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLE 696
            ....|.......|||:||:.||:....|:..||:|.||:.:|||:.||..|:.|:..:||:.|:.
  Fly   637 TSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVR 701

  Fly   697 NGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEIL 740
            :|.||..|.:|...||::|..||:::|.:||.|..|.:.|.::|
  Fly   702 DGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fak	NP_001137718.1	B41	24..267	CDD:214604
		FERM_B-lobe	152..257	CDD:271216
		FERM_C_FAK1	263..394	CDD:270011	21/85 (25%)
		PTKc_FAK	450..744	CDD:133187	98/351 (28%)
		Focal_AT	1250..1376	CDD:460992
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		PTKc	474..742	CDD:270623	82/267 (31%)