Protein Alignment Fak and btl

DIOPT Version :10

• Sequence 1: NP_001137718.1
• Gene: Fak / 37233
• FlyBaseID: FBgn0020440
• Length: 1500
• Species: Drosophila melanogaster
• Sequence 2: NP_729956.1
• Gene: btl / 39564
• FlyBaseID: FBgn0285896
• Length: 1052
• Species: Drosophila melanogaster
• Alignment Length: 390
• Identity: 110/390 - (28%)
• Similarity: 181/390 - (46%)
• Gaps: 61/390 - (15%)

  Fly   437 EGEGDYSTPTVRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNA 501
            :|..:|..|...|:|:.|..::..:.:|.|.||.|.:                      ::....
  Fly   692 QGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVM----------------------AEAEGL 734

  Fly   502 DSRPDVIQ--VAIKTCKANDDPEKTENFLAEAYIMQKF-DHPHIIRLIGICSV-MPIWIVMELAK 562
            ...|.:.:  ||:|..|.........:.:.|..:|:.. .|.:||.|:|.||. .|:|:::|.|.
  Fly   735 PRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAP 799

  Fly   563 LGELRAYLKTN----------------------SERLSHGTLLKYCYQLSTALSYLESKKFVHRD 605
            .|.|:.:||.|                      ::.|....|.|:.:|::..:.||.|::.:|||
  Fly   800 HGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRD 864

  Fly   606 IAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGV 670
            :||||||||....:|:|||||:|.:.|..||.......||||||:|||:..:::.:.||||.:||
  Fly   865 LAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGV 929

  Fly   671 CIWEILMLGVKPFQGVKNSDVILK-LENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKE 734
            .:|||:..|.:|:..:.:::.:.. |..|:|:..|..|...:|.:|.|||.:|...||.|..:.|
  Fly   930 LLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVE 994

  Fly   735 TLHEILIEDSINSSETLKREQRKVASMSWIGSDDIDIPPSKPSRVMHDPDITGLMPETTGLPQTY 799
            :...||.:.|.|.::....          :....::.|||....  .|...|....||:.|...|
  Fly   995 SFDGILQQASSNPNDAYLD----------LSMPMLETPPSSGDE--DDGSDTETFRETSPLRYQY 1047

  Fly   800  799
              Fly  1048  1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fak	NP_001137718.1	B41	24..267	CDD:214604
		FERM_B-lobe	152..257	CDD:271216
		FERM_C_FAK1	263..394	CDD:270011
		PTKc_FAK	450..744	CDD:133187	95/320 (30%)
		Focal_AT	1250..1376	CDD:460992
btl	NP_729956.1	Ig	143..215	CDD:472250
		Ig strand B	160..164	CDD:409570
		Ig strand C	175..179	CDD:409570
		Ig strand E	197..201	CDD:409570
		Ig strand F	211..215	CDD:409570
		Ig_3	247..333	CDD:464046
		Ig	398..479	CDD:472250
		Ig strand B	412..416	CDD:409393
		Ig strand C	423..427	CDD:409393
		Ig strand E	445..449	CDD:409393
		Ig strand F	459..464	CDD:409393
		Ig strand G	472..475	CDD:409393
		IG_like	492..583	CDD:214653
		Ig strand B	503..507	CDD:409444
		Ig strand C	516..520	CDD:409444
		Ig strand E	549..553	CDD:409444
		Ig strand F	563..568	CDD:409444
		Ig strand G	576..579	CDD:409444
		Protein Kinases, catalytic domain	700..1000	CDD:473864	95/321 (30%)