Protein Alignment Fak and Src42A

DIOPT Version :9

• Sequence 1: NP_001137718.1
• Gene: Fak / 37233
• FlyBaseID: FBgn0020440
• Length: 1500
• Species: Drosophila melanogaster
• Sequence 2: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 152/552 - (27%)
• Similarity: 238/552 - (43%)
• Gaps: 144/552 - (26%)

  Fly   292 QTHPQASLKNVAQFKDVVSIKTCTLPKEKLSKSGENTTEPELQNFNCNCQKIKTQIKISASNNVE 356
            |.|.|..|.......:.:.:.:.|..::.|.:....|.      ..|.|.....::.::|.....
  Fly  1092 QQHQQTPLAKKHSLDNCLQVVSSTTSRQPLRRWSNQTP------LKCTCHPATEELPLTAIEKSR 1150

  Fly   357 DLVITCNGINTAESIADL--ID-------------------GYCRLLSKDLEFT--------IWH 392
            .|...|:. :.:.:.|.|  ||                   |..|.||   |||        .|:
  Fly  1151 SLPAACSA-SCSHTCAHLSVIDQSPATTKCFGKTSLTTAKKGKSRRLS---EFTRGEFLNEKSWY 1211

  Fly   393 -------------------------RETNASNEDSAKALPNDAT--------------------- 411
                                     |::.:.:.|.:.::.:..|
  Fly  1212 FRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGFFIARRTT 1276

  Fly   412 ------LGSNKSTSSQG------KPMLTDDYAEIGLLEGEGDYSTPTVRNYELDRALITPSAKIG 464
                  |..:.|..|.|      ||.:   ..|..:.||   .|..|...:|:||..:....|:|
  Fly  1277 FRTLQELVEHYSKDSDGLCVNLCKPCV---QIEKPVTEG---LSHRTRDQWEIDRTSLKFVRKLG 1335

  Fly   465 VGQFGDVYVGTY--TLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKAND-DPEKTEN 526
            .||||||:.|.:  |.|                              |||||.|:.. ||   ::
  Fly  1336 SGQFGDVWEGLWNNTTP------------------------------VAIKTLKSGTMDP---KD 1367

  Fly   527 FLAEAYIMQKFDHPHIIRLIGICSV-MPIWIVMELAKLGELRAYLKT---NSERLSHGTLLKYCY 587
            |||||.||:|..|..:|:|..:|:| .||:|:.||.|.|.|..||:.   ....|...||:....
  Fly  1368 FLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAA 1432

  Fly   588 QLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPE 652
            |::..::||||:.::|||:|||||||.....||:|||||:|.:.:.. |.:......||||.:||
  Fly  1433 QIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDE-YEARVGARFPIKWTAPE 1496

  Fly   653 SINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQ 717
            :.|:.:|:..||||.||:.:.|::..|..|:.|:.|::|:.::|:|.|:|.||||.||||.:|.:
  Fly  1497 AANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLE 1561

  Fly   718 CWAYEPLKRPNFKRIKETLHEILIEDSINSSE 749
            ||..:|::||.|:.::..|.:....|..:..|
  Fly  1562 CWHKDPMRRPTFETLQWKLEDFYTSDQSDYKE 1593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fak	NP_001137718.1	B41	24..267	CDD:214604
		FERM_B-lobe	152..257	CDD:271216
		FERM_C_FAK1	263..394	CDD:270011	24/155 (15%)
		PTKc_FAK	450..744	CDD:133187	112/300 (37%)
		Pkinase_Tyr	462..736	CDD:285015	108/280 (39%)
		Focal_AT	1249..1376	CDD:281606
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	8/90 (9%)
		PTKc_Frk_like	1319..1587	CDD:270653	112/301 (37%)
		Pkinase_Tyr	1328..1580	CDD:285015	108/285 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468394
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840