| Sequence 1: | NP_001137718.1 | Gene: | Fak / 37233 | FlyBaseID: | FBgn0020440 | Length: | 1500 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006520478.1 | Gene: | Ptk2 / 14083 | MGIID: | 95481 | Length: | 1140 | Species: | Mus musculus |
| Alignment Length: | 1382 | Identity: | 432/1382 - (31%) |
|---|---|---|---|
| Similarity: | 622/1382 - (45%) | Gaps: | 415/1382 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 48 IRRTVEDLGTDGRTPSIQRYACRMLNMITKEVIWLARSTSMQKVLSHILTPGCSNVDCPNNQSEL 112
Fly 113 DEVLLEHGRRITDNRVWRVELRVRYVPNNIQELFEEDKATCFYYFNQVKEDFIQANVTAIDTEVA 177
Fly 178 VQLCCLGIRHYFKNITVKAPDKKQHIDYIEKEIGFKSFLPQSVIATSKPKNLKKLIQVGYKKVYN 242
Fly 243 YNDIEYLTRFFDLLKNIYLTNFEQFSVTLSSAWNISGILHVGPHIGISYQTHPQASLKNVAQFKD 307
Fly 308 VVSIKTCTLPKEKLSKSGENTTEPELQNFNCNCQKIKTQIKISASNNVEDLVITCNGINTAESIA 372
Fly 373 DLIDGYCRLLSKDLEFTIWHRETNASNEDSAKALPNDATLGSNK-------STSSQG-------- 422
Fly 423 ------KPML----------------TDDYAEIGLLEGEGDYSTPT-------VRNYELDRALIT 458
Fly 459 PSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEK 523
Fly 524 TENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQ 588
Fly 589 LSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPES 653
Fly 654 INFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQC 718
Fly 719 WAYEPLKRPNFKRIKETLHEILIEDSINSSETLKREQRKVASMSWI--GSDDIDIPPSKPSRVMH 781
Fly 782 DPDITGLMPETTGLPQTYIIAQNPAVLAKLMMENQKRGINPAAYTTPASVFNTLAVGLDDSNPNV 846
Fly 847 SLKTTKLPAADLLKLDPIAESERLRSQFSANSSASQLANPLTASVNPHESLNSHQAGMFTGSLPS 911
Fly 912 KSSFVVCPPQTEEHMQAENISNPSVSKVSGYSLYGSLERHQPPPAKAMHSKGGSLERHQ-SLMSA 975
Fly 976 QNLVFYNTKPPPNCTNTAERSRSMERNTYFHAYRQQMKTSIECEALPEEIYDFGGIGLKTCVSAR 1040
Fly 1041 QQPKFSPMVNVRPAELGQVQNTDCMGLQQNIPMDSFGVISPHNLDESL-RHQREME--RQWMTSG 1102
Fly 1103 PQSITVNPNISISEGAACLATLQAEAMGNQGIHNVLGEKLRQQQKDSNSDSEWLIQEELLRSCSI 1167
Fly 1168 PQGSLNDHQAQMFKLDFMSAGPSSLPDCSNSSSRPMTPNA--NLSSLKSNHSSADHLSSLTSAEE 1230
Fly 1231 QMGSNARNLGSAVPSRPP----NRADDEVYCATTLVVKSIMALSQGVEKANTEGYLELVKNVGVK 1291
Fly 1292 LRNLLTSVDKISIIFPAQALKEVQMAHQVLSKDMHELVSAMRLAQQYSDTTLDCEYRKSMLSAAH 1356
Fly 1357 VLAMDAKNLFDVVDSIR 1373 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Fak | NP_001137718.1 | B41 | 24..267 | CDD:214604 | 63/218 (29%) |
| FERM_B-lobe | 152..257 | CDD:271216 | 36/104 (35%) | ||
| FERM_C_FAK1 | 263..394 | CDD:270011 | 40/130 (31%) | ||
| PTKc_FAK | 450..744 | CDD:133187 | 168/293 (57%) | ||
| Pkinase_Tyr | 462..736 | CDD:285015 | 160/273 (59%) | ||
| Focal_AT | 1249..1376 | CDD:281606 | 58/125 (46%) | ||
| Ptk2 | XP_006520478.1 | FERM_N_2 | 79..174 | CDD:407875 | 19/90 (21%) |
| B41 | 80..302 | CDD:214604 | 63/218 (29%) | ||
| FERM_C_FAK1 | 298..408 | CDD:270011 | 40/136 (29%) | ||
| PTKc_FAK | 500..769 | CDD:133187 | 168/293 (57%) | ||
| Focal_AT | 1004..1133 | CDD:397606 | 58/127 (46%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 324 | 1.000 | Domainoid score | I1198 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4257 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H7314 | |
| Inparanoid | 1 | 1.050 | 653 | 1.000 | Inparanoid score | I777 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3805 |
| OMA | 1 | 1.010 | - | - | QHG46813 | |
| OrthoDB | 1 | 1.010 | - | - | D29350at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002650 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44146 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105566 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4950 |
| SonicParanoid | 1 | 1.000 | - | - | X1755 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 15 | 14.720 | |||||