Protein Alignment Fak and ptk6

DIOPT Version :10

• Sequence 1: NP_001137718.1
• Gene: Fak / 37233
• FlyBaseID: FBgn0020440
• Length: 1500
• Species: Drosophila melanogaster
• Sequence 2: XP_002942429.3
• Gene: ptk6 / 100490792
• XenbaseID: XB-GENE-22069031
• Length: 563
• Species: Xenopus tropicalis
• Alignment Length: 301
• Identity: 101/301 - (33%)
• Similarity: 162/301 - (53%)
• Gaps: 34/301 - (11%)

  Fly   441 DYSTPTVRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRP 505
            |.|...:..:|..|...|...::|:|.||.|:.|      |.|||
 Frog   271 DLSPVPLDEWERPREEFTLVKRLGMGNFGQVHEG------LWKGK-------------------- 309

  Fly   506 DVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSV-MPIWIVMELAKLGELRAY 569
              ::||:||.|.  |....:.|:.|...::...|.:::.|..:||| .|.:||.||...|:|..|
 Frog   310 --LKVAVKTIKR--DATSQDLFVKETAFLKTLHHKNLLSLYAVCSVGDPYYIVTELVPRGDLLNY 370

  Fly   570 LK-TNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQ 633
            |: ...:.|.....|....|::..:.||||:..:|||:||||||:......|:||||::|.:.|
 Frog   371 LRDLEKDELDVEGQLDIATQVAEGMRYLESQNCIHRDLAARNVLMGRNNICKIADFGMARVILD- 434

  Fly   634 SYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENG 698
            |||.|. :..:|.||.:||::.:.|:|..||||.||:.::||:.||::|:..:.|.:|:..|..|
 Frog   435 SYYVSA-SKEIPFKWTAPEAVEYGRYTVKSDVWSFGILLYEIMSLGMQPYPALSNYEVLEFLNRG 498

  Fly   699 ERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEI 739
            :|:..||:|..|:|::|..|||:.|.:||:|..::..|..:
 Frog   499 QRMKAPPSCSTRVYNIMLTCWAWNPNERPSFDDLRTMLENL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fak	NP_001137718.1	B41	24..267	CDD:214604
		FERM_B-lobe	152..257	CDD:271216
		FERM_C_FAK1	263..394	CDD:270011
		PTKc_FAK	450..744	CDD:133187	99/292 (34%)
		Focal_AT	1250..1376	CDD:460992
ptk6	XP_002942429.3	SH3	104..161	CDD:473055
		SH2	168..252	CDD:214585
		STYKc	288..536	CDD:214568	96/279 (34%)