Protein Alignment CalpA and Capn15

DIOPT Version :9

• Sequence 1: NP_001286613.1
• Gene: CalpA / 37232
• FlyBaseID: FBgn0012051
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001334263.1
• Gene: Capn15 / 50817
• MGIID: 1355075
• Length: 1196
• Species: Mus musculus
• Alignment Length: 548
• Identity: 148/548 - (27%)
• Similarity: 216/548 - (39%)
• Gaps: 131/548 - (23%)

  Fly    90 YETILNSCLASGSLFEDPLFPASNESLQF---SRRPDRHIEWLRPHEIAENPQFFVE---GYSRF 148
            :|.|:..|..:...|.|..||....|:.|   .....|..:|||||||  |...|.:   .:|.|
Mouse   550 WENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEI--NCSVFRDHGTPWSVF 612

  Fly   149 ------DVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVII 207
                  |:.||.||:||.|:|.|.|.:..:|..||:.......|   |.:..|..:.|.|..|::
Mouse   613 HTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAE---GAYQVRLCKDGTWTTVLV 674

  Fly   208 DDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKE 272
            ||.||......:.....::.:.|.||:|||.|||||||.||:.|...|.:...||...|...|:.
Mouse   675 DDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQV 739

  Fly   273 APGN----------LFTILQKAAERNSMMGCS-----IEPDPNVTEAETPQGLIRGHAYSITKVC 322
            :..|          ::..:..:.|...:||.|     ::.|....|:   .||...||||:..|
Mouse   740 SSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYES---LGLRPRHAYSVLDV- 800

  Fly   323 LIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQ 387
             .|:     ||. .::|:||||| ...|||.|||..|.|   |...:||:......:|.|||.:.
Mouse   801 -RDV-----QGS-RLLRLRNPWG-RFSWNGSWSDEWPHW---PGHLRAELMPHGSSEGVFWMEYS 854

  Fly   388 DFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIIT 452
            ||:.:||.|:||.:..|             |:.:..:|.:..  ||||           |..:..
Mouse   855 DFIRYFDSVDICKVHSD-------------WQEARVQGCFPS--TAGG-----------PVGVTA 893

  Fly   453 LVDPDEEDEEGQCTVIVALMQKNRRSKRNMGME----CLTIGFAIYSLNDRELENRPQGLNFFRY 513
            |...:....|      .||.|:..|...::...    |:.:..|.:....|
Mouse   894 LTVLERASLE------FALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGR-------------- 938

  Fly   514 KSSVGRSPHFINTREVCARF-----KLPPGHYLIVPSTFD------PNEEGEFIIRVFSETQNNM 567
             .|:||.  ..:::....:|     .|.||.|.:|...|:      |....:
Mouse   939 -LSLGRL--LAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQ------------- 987

  Fly   568 EENDDHVGYGGKADTITPGFPTPKPIDP 595
                   |.|......||.|||.:|..|
Mouse   988 -------GKGPSQMRPTPSFPTSEPQSP 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpA	NP_001286613.1	Peptidase_C2	104..400	CDD:279042	107/322 (33%)
		Calpain_III	418..565	CDD:279416	27/161 (17%)
		EFh	719..765	CDD:238008
Capn15	NP_001334263.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920