Protein Alignment CalpA and capn5

DIOPT Version :9

• Sequence 1: NP_001286613.1
• Gene: CalpA / 37232
• FlyBaseID: FBgn0012051
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001006736.1
• Gene: capn5 / 448405
• XenbaseID: XB-GENE-947203
• Length: 642
• Species: Xenopus tropicalis
• Alignment Length: 663
• Identity: 236/663 - (35%)
• Similarity: 350/663 - (52%)
• Gaps: 107/663 - (16%)

  Fly    79 SSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHEIAENPQFFVE 143
            ||..|:.. |.|:.:...|.:...|||||:|||:|::|.:..:..:.::|.||.|...:|..||:
 Frog     3 SSAKPFGN-QQYQALKKECQSKKVLFEDPVFPANNDALFYKTQRVQGVQWKRPKEFCTDPHLFVD 66

  Fly   144 GYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIP--AEQSF----EENYAGIFHFRFWQYGKW 202
            |.|..|:.||::|:||.:||.::|.....|:.:|||  .||.:    .:.|||||||.||::|:|
 Frog    67 GISSHDLHQGQVGNCWFIAACSSLASREQLWQKVIPDWKEQEWYADKPQIYAGIFHFHFWKFGEW 131

  Fly   203 VDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEW 267
            |||:|||||||.|.:|:|.||.||||.|.||:|||||||.|.||||.||:|.:|:.||||||||.
 Frog   132 VDVVIDDRLPTINNQLIYCHSNEKNELWCALVEKAYAKLAGCYEALDGGNTADALVDFTGGVSEP 196

  Fly   268 YDLKEA--------PGNLFTILQKAAERNSMMGCSIE-PDPNVTEAETPQGLIRGHAYSITKVCL 323
            .:|.|.        ..:||..:.|...|..::.|||. ...:..||....||::||||::|.|..
 Frog   197 IELTEGHFVTDVEKRNDLFERVLKVHNRGGLISCSIRATSASDMEARMACGLVKGHAYAVTDVRK 261

  Fly   324 I----DIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWM 384
            :    .::...:..|:.||||||||| |.||||||||||.||:.:.:.::.::|:|.:.||||||
 Frog   262 VRLGHGLLAFFKSEKLEMIRMRNPWG-EREWNGPWSDSSEEWQKVSKSEREKLGVTVEDDGEFWM 325

  Fly   385 SFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGV-----TAGGCRNFLDTFW 444
            :|:||..::..:.:|.|...|..     |..:.||.::....|....     .:|||.||..|:.
 Frog   326 TFEDFCKYYTDIIMCRLINTSYL-----SIHKTWEEAVLRSSWVQHQDPLQNRSGGCLNFKATYL 385

  Fly   445 HNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMG-MECLTIGFAIYSLNDRELENRPQGL 508
            .|||::..:..|::|       |:|.|.||.:|:.|..| .|.|.|||.|:.:   ||..|
 Frog   386 QNPQFVFDVKKPEDE-------VLVCLQQKTKRTTRQEGKAENLAIGFEIHQV---ELNRR---- 436

  Fly   509 NFFRYKSSVGR--SPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEEND 571
              ||..:...:  |..:||:|.|..|..|..|.|:|:|:||||...|||::|||::..:|..|.
 Frog   437 --FRMHTLQPKVASSIYINSRCVFLRTDLKEGRYVIIPTTFDPGHTGEFLLRVFTDLPSNCCEL- 498

  Fly   572 DHVGYGGKADTITP-------GFP--TPKPIDPQKEGLRRLFDSIAGKDMEV------------- 614
                   |.|..|.       |:|  ..:......:||::. ||..|.|..|
 Frog   499 -------KLDEPTKTCWSGLCGYPQLVSQVHVVSAQGLKQQ-DSNGGADPYVIISCEGNKVQSPV 555

  Fly   615 --DWMELK------------------RILDHS-MRDDLPKPVVFNRFSNNM----AFETQAAGPG 654
              |.::.|                  ::.:|: ::|:....||.:..:||:    :.|.|..|..
 Frog   556 IKDCLDPKFNVKGVFYRKKPGQPIVVQVWNHNVIKDEFMGLVVLSGDANNLQTQHSLELQDKGNK 620

  Fly   655 DDGAGACGLLSLI 667
            ..|. ..|.::|:
 Frog   621 KSGT-VSGTINLV 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpA	NP_001286613.1	Peptidase_C2	104..400	CDD:279042	143/314 (46%)
		Calpain_III	418..565	CDD:279416	54/154 (35%)
		EFh	719..765	CDD:238008
capn5	NP_001006736.1	Peptidase_C2	27..341	CDD:395523	143/314 (46%)
		Calpain_III	362..488	CDD:395848	50/141 (35%)
		C2_Calpain	515..640	CDD:176011	22/120 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	1	1.000	-	-		FOG0000071
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X74
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010