Protein Alignment CalpA and Capn7

DIOPT Version :9

• Sequence 1: NP_001286613.1
• Gene: CalpA / 37232
• FlyBaseID: FBgn0012051
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001025208.1
• Gene: Capn7 / 306260
• RGDID: 1304855
• Length: 813
• Species: Rattus norvegicus
• Alignment Length: 637
• Identity: 134/637 - (21%)
• Similarity: 219/637 - (34%)
• Gaps: 255/637 - (40%)

  Fly    97 CLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLL 161
            |...|.|   ||.|  .:...||:       |:||.::..||. .:...|.|.::|..:.||..:
  Rat   242 CDRLGKL---PLSP--KQKATFSK-------WVRPEDLTNNPT-MIYTVSSFSIKQTIVSDCSFV 293

  Fly   162 AATANLTQESNLFFR------VIPAEQSFEENY--AGIFHFRFWQYGKWVDVIIDDRLPT-YNGE 217
            |:.|........|.:      :.|..:..|..|  .|.:..:....|....|||||:||. :.||
  Rat   294 ASLAISAAYERRFNKKLITSIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGE 358

  Fly   218 LMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKE-----APGNL 277
            |:..:|..|:|.|.:|:||||.|:.|.|: ..|.::...:...||.:.|...:..     :..:.
  Rat   359 LLCSYSNNKSELWVSLIEKAYMKVMGGYD-FPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDSS 422

  Fly   278 FTILQKAAERNSMM-----GCSIEPDPNVTEAETPQ-GLIRGHAYSITKVCLIDIVTPNRQGK-I 335
            |.:|.:...:..::     |.       :||||..: ||:..|||::     :||    |:.| :
  Rat   423 FRMLYQRFHKGDVLITASTGM-------MTEAEGEKWGLVPTHAYAV-----LDI----REFKGL 471

  Fly   336 PMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFD-------RDGEFWMSFQDFLNHF 393
            ..|:::||| :...|.|.:|::..: .:.||.||.   |.||       .:|.||:|:.|...::
  Rat   472 RFIQLKNPW-SHLRWKGRYSENDVK-NWTPELQKY---LNFDPRTAQKIDNGIFWISWDDLCQYY 531

  Fly   394 DRV------------------------------EICNLSPDSLTEDQ------------------ 410
            |.|                              .:.| :|....|.|
  Rat   532 DVVYLSWNPALFKESTCIHSTWDAKQGPVKDAYSLAN-NPQYKLEVQCPQGGAAVWVLLSRHITD 595

  Fly   411 ----------------QNSGKRKW-----------------------------------EMSMYE 424
                            :..||:.:                                   .:|.||
  Rat   596 KDDFANNREFITMVVYKTDGKKVYYPADPAPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYE 660

  Fly   425 ---------------------------------GEWTPGVTAGGCRNFLDTFWHNPQYIITLVDP 456
                                             |:|: |.:||||.||.:|..:||.|...:
  Rat   661 KQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWS-GQSAGGCGNFQETHKNNPIYQFHI--- 721

  Fly   457 DEEDEEGQCTVIVALMQKNRRSKRNMGMECLTI---------GFAIYSLND-------RELENRP 505
               |:.|.     .|::.....:.::|.|.:.:         ||...|..|       .||||
  Rat   722 ---DKTGP-----LLIELRGPRQYSVGFEVVAVSIAGDPGPHGFQRKSSGDYRCGFCYLELEN-- 776

  Fly   506 QGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFII 557
                                         :|.|.:.::||||.|.:||.|.:
  Rat   777 -----------------------------IPAGIFNVIPSTFLPKQEGPFFL 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpA	NP_001286613.1	Peptidase_C2	104..400	CDD:279042	86/353 (24%)
		Calpain_III	418..565	CDD:279416	39/224 (17%)
		EFh	719..765	CDD:238008
Capn7	NP_001025208.1	MIT_calpain7_1	5..76	CDD:239144
		MIT	85..157	CDD:412291
		CysPc	214..538	CDD:238004	89/330 (27%)
		calpain_III	687..810	CDD:214786	36/156 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810