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Protein Alignment CalpA and Capn9

DIOPT Version :10

Sequence 1:	NP_001286613.1	Gene:	CalpA / 37232	FlyBaseID:	FBgn0012051	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_001258069.1	Gene:	Capn9 / 116694	RGDID:	70965	Length:	690	Species:	Rattus norvegicus

Alignment Length:	763	Identity:	324/763 - (42%)
Similarity:	462/763 - (60%)	Gaps:	102/763 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 YSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHEIAENPQFFVEGYSRF 148
            :|....:|.:..|||.||:||||..|||||.||.:|.||.....|.||.||.|||:|.:.|.:|.
  Rat    23 HSSGHSFEQLRQSCLQSGTLFEDADFPASNSSLFYSERPQVPFVWKRPGEIVENPEFILGGATRT 87

  Fly   149 DVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLPT 213
            |:.||||||||||||.|:||.......||:|.:|.|...|||||||:|||:.:|:||:|||||||
  Rat    88 DICQGELGDCWLLAAIASLTLNQKALARVVPQDQGFGSGYAGIFHFQFWQHSEWLDVVIDDRLPT 152

  Fly   214 YNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEAPGNLF 278
            :...|:::||.:.|||||||||||||||:||||||||||..||||||||||:|.:.::|||.:.:
  Rat   153 FRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAENFQIREAPEDFY 217

  Fly   279 TILQKAAERNSMMGCSIEP-DPNVTEAETPQGLIRGHAYSITKVCLIDIVTPNRQGKIPMIRMRN 342
            .||:||..|.|::||||:. :.:.:||.||.|||:||||::|.   :|.|..:.| :|.:||:||
  Rat   218 EILEKALRRGSLLGCSIDTLNASESEARTPLGLIKGHAYTVTG---LDQVNFHGQ-RIKLIRVRN 278

  Fly   343 PWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLT 407
            ||| :.||||||||||||||.:..|::..:|.|...||||||:|:||..|||:||||||:||:|
  Rat   279 PWG-QVEWNGPWSDSSPEWRSMSLEEQKRLGHTALDDGEFWMAFEDFKTHFDKVEICNLTPDAL- 341

  Fly   408 EDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALM 472
               :::...|||:::::|.|..|.|||||||||||||.|||..::|.:.| |.:|| ||.:.|||
  Rat   342 ---EDNTLHKWEVTIHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTERD-EGQEG-CTFLAALM 401

  Fly   473 QKNRRSKRNMGMECLTIGFAIYSLNDRELE-NRPQGLNFFRYKSSVGRSPHFINTREVCARFKLP 536
            ||:||..:..|...||||:|||...|::.. ||    :||||.:|:.||..|||.|||..||:||
  Rat   402 QKDRRRLKRFGANMLTIGYAIYQCPDKDGHLNR----DFFRYHASLARSKTFINLREVSGRFQLP 462

  Fly   537 PGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKPIDPQKE--- 598
            ||.|:::||||:|::|.:|.:|:|||.:...::.|:::      |...|..|.|.|.:.:.|
  Rat   463 PGDYILIPSTFEPHQEADFCLRIFSEKKAVTQDLDENI------DIDLPELPKPTPQEEETEEER 521

  Fly   599 GLRRLFDSIAGKDMEVDWMELKRILDHSMRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGL 663
            ..|.||..|||:||||...||:.:|:..::.  ...:.|.|.|                     |
  Rat   522 QFRALFRRIAGEDMEVSAEELEYVLNAVLQK--KTALKFKRLS---------------------L 563

  Fly   664 LSLICGPFLKGTPFEEQLGMNDQSNKRLIGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDA 728
            ||                                                     ||::::::|.
  Rat   564 LS-----------------------------------------------------CRNIISLMDT 575

  Fly   729 DKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYG 793
            ..:||:.||||.....::..|..:|..:||:.:|.:|.::||.||.:||:.|.:.:|.::..||.
  Rat   576 SGNGKMEFEEFRVFWDKLRYWMDLFLQFDVDKSGTMSSYELRTALKAAGFQLGSHLLQLIVLRYA 640

  Fly   794 SRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIERTI 841
            ..:.::.|||::.|.|:::....:|:....:..:.....:.|:|..|:
  Rat   641 DENLQLDFDDYLNCLVRLENASRVFQCLSVKNKDFIHLNINEFINLTM 688

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.