Protein Alignment CalpA and LOC100495980

DIOPT Version :9

• Sequence 1: NP_001286613.1
• Gene: CalpA / 37232
• FlyBaseID: FBgn0012051
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: XP_017952054.2
• Gene: LOC100495980 / 100495980
• -ID: -
• Length: 737
• Species: Xenopus tropicalis
• Alignment Length: 804
• Identity: 308/804 - (38%)
• Similarity: 442/804 - (54%)
• Gaps: 138/804 - (17%)

  Fly    61 LQSQSNSTLYYGNLGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSR----- 120
            ||.:.||:..:        ::.||.. |||..::..||....|||||.|||.::||.::.
 Frog    10 LQKEENSSARH--------NVSPYLG-QDYHRLVQECLKQRQLFEDPHFPAKSKSLGYNELGPFS 65

  Fly   121 RPDRHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFE 185
            ...:.|:|.||.||.::|||..|.....||.|||||:||.|||.|:|||...|..||:|.:|||:
 Frog    66 ENTKGIQWRRPQEICQSPQFICEDMKWTDVCQGELGNCWFLAAAASLTQYPLLKERVVPPQQSFK 130

  Fly   186 ENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKG 250
            ..|||||||:|||||:||||::|||||...|||:::.|.:|:|||:||||||||||:||||||.|
 Frog   131 SGYAGIFHFQFWQYGEWVDVVVDDRLPVKEGELVFVSSAQKSEFWAALLEKAYAKLNGSYEALNG 195

  Fly   251 GSTCEAMEDFTGGVSEWYDLKEAPGNLFTILQKAAERNSMMGCSIEP-DPNVTEAETPQGLIRGH 314
            |...||..|||||:.|...|||.|.|||.:||||.::.|:||..|:| ..:..|.:||:||:.||
 Frog   196 GFMNEAFVDFTGGLGETVKLKETPPNLFHLLQKAVKKKSLMGAFIQPQSQSQIENQTPEGLLTGH 260

  Fly   315 AYSITKVCLIDIVT---PNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTF 376
            ||||       |.|   .|...|||::|:||||| ..||||.|||.|..|..:..|.:.::.:.
 Frog   261 AYSI-------IATWEMKNNGKKIPLLRLRNPWG-RVEWNGHWSDDSTLWSQVDPEIRKKLQVR- 316

  Fly   377 DRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLD 441
            ..||||||..:|||..||.:|:|||:|:|:|:..    .:.|:.:.:.|.|. |.:|||||.:.|
 Frog   317 GEDGEFWMQMEDFLRFFDILEVCNLTPESVTDKH----AQLWKTNTFCGRWL-GHSAGGCRTYKD 376

  Fly   442 TFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFAIYSLNDRELENR-- 504
            |||.|||:::||.:.||| :.|.||::|:|||||||..|::|.:.|::||.||.: .:|.:|:
 Frog   377 TFWTNPQFLVTLTEQDEE-KHGMCTLLVSLMQKNRRQCRSIGQDFLSVGFEIYQV-PKEFDNKMC 439

  Fly   505 -PQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNME 568
             .:..|.|....||. |..|::.|:|..|::||||.||::||||.|::|.:||:|:|:|.|:...
 Frog   440 ASERKNLFSSLVSVA-SCSFMDERDVTGRYQLPPGRYLLIPSTFQPHQESDFIMRIFTEKQHTFI 503

  Fly   569 ENDDHVGYGGKA-------DTITPGFPTPKPIDPQKEGLRRLFDSIAGKDMEVDWMELKRILDHS 626
            |.|..:...|..       ||:              |.....|..::|:|.|:...||:|||..
 Frog   504 EIDCEIRANGNVFKENALKDTM--------------EEFSAQFARLSGEDQEISPEELQRILIQ- 553

  Fly   627 MRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGLLSLICGPFLKGTPFEEQLGMNDQSNKRL 691
                                                                             
 Frog   554 ----------------------------------------------------------------- 553

  Fly   692 IGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVY 756
                      :|:.....:|:|||.|:||.:|.|:|.:.:|||..|||..|.|:|.:|:.||..|
 Frog   554 ----------ITSKNTHLKTNGFSLDICRKLVKMVDLNCNGKLQLEEFRKLWSKIKEWEKIFTNY 608

  Fly   757 DVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKER 821
            |.:.:|.:...:|..||.:||:.|||:::..|..:||:...::.||.|:.|...:....:..:..
 Frog   609 DKDRSGTMDVQELCLALEAAGFTLNNQLVESLCQKYGNNVRQVYFDSFLSCLAYLVCVFEQCRIM 673

  Fly   822 DTEKNETATFTLEE---WIERTIY 842
            |..|:.....:.||   :|:.|||
 Frog   674 DKNKDGVICISKEEASIYIKGTIY 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpA	NP_001286613.1	Peptidase_C2	104..400	CDD:279042	158/304 (52%)
		Calpain_III	418..565	CDD:279416	67/149 (45%)
		EFh	719..765	CDD:238008	20/45 (44%)
LOC100495980	XP_017952054.2	Peptidase_C2	44..340	CDD:395523	158/304 (52%)
		Calpain_III	361..495	CDD:395848	64/137 (47%)
		EFh_PEF	527..687	CDD:355382	52/235 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D87342at33208
OrthoFinder	1	1.000	-	-		FOG0000071
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X74
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010