Protein Alignment hts and add2

DIOPT Version :10

• Sequence 1: NP_001097377.2
• Gene: hts / 37230
• FlyBaseID: FBgn0263391
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001352363.2
• Gene: add2 / 570147
• ZFINID: ZDB-GENE-080718-4
• Length: 669
• Species: Danio rerio
• Alignment Length: 691
• Identity: 225/691 - (32%)
• Similarity: 345/691 - (49%)
• Gaps: 127/691 - (18%)

  Fly     3 EVEQPPQNGIDPTAGEDDDNSKARPADIEQDMREMERRKRVEAIMGSKLFREELERIVDSARDGG 67
            |:.|.||.. .|::|                     .:|||.:::.|..|||||:.::......|
Zfish    25 EMIQSPQQS-TPSSG---------------------LKKRVSSLLQSPSFREELDVLIQEQMKKG 67

  Fly    68 AGASGI--LQQLSDIV---GVPVSRVGSVFKSSNCMVPINDIRGVESMGYAKGEKILRCKLAATF 127
            ..:|.:  |:|::|.:   |.|.:...:...:...:.||||:.|.|.....|||:::|||||:..
Zfish    68 GSSSNLWALRQIADFMATHGSPAALPVTPSTAVTIVTPINDLHGWEPSSMVKGERLMRCKLASVH 132

  Fly   128 RLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNK 192
            ||||||||.|.....:|.|:..:||:|||.|.||.|.|:|||:|.||::.|::||:|:|....:.
Zfish   133 RLLDLYGWAQLANTCLTMRVSKEQEHFLVLPDGLAYGEVTASSLVKVNILGEVVEKGSTALAVDL 197

  Fly   193 SHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLGEITTHAYTGLFDEEE-R 256
            |.|.|||.:::||||:||.:::......|:|::|.|||||:.:|.::||:..:.|.|:.:||| |
Zfish   198 SSFSLHSAIYSARPDVRCLLHLHTPATAAVSAMKCGLLPLSHEALLVGEVAYYDYNGVMEEEEDR 262

  Fly   257 NRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLL--PVGLDNLVLIPEES 319
            ..|.:||||..||::|.|||.:..||::||||:...||..||:.|:..|  ..|..||:::....
Zfish   263 VELQKSLGPTCKVLVLRNHGIVALGESVEEAFYTIYHIQTACQIQVAALCSAGGEQNLIMLDRNV 327

  Fly   320 RKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDN 384
            .:.:                           |:.....|....|...|.|:|..|||||||.|||
Zfish   328 HRPV---------------------------AKGTVGWAGSTFGPMQKSRLGEHEFEALMRTLDN 365

  Fly   385 AGYRTGYIYRHPLIKSDPPKPKNDVELPPAVSSLGYLLEEEELFRQGIWKKGDI----RKGGDRS 445
            .||||||.||.|:: .:..:.:.:||:|..|:|..:       ...|:.....:    ::...::
Zfish   366 LGYRTGYAYRFPVL-LERSRTRREVEVPATVTSFSF-------HEDGVQPHPRLHPHTQRQQQKT 422

  Fly   446 RWLNSPNVYQKVEVLETGTPDPKKITKW-----VAEGSPTHSTPVRIEDPLQFVPAGTNPREFKR 505
            ||||:|||||||   ......|...|.|     :.:||   ...::||:|.||||..|||:|...
Zfish   423 RWLNTPNVYQKV---NQDQASPGHRTTWQKSEEITQGS---GRAIKIENPNQFVPLFTNPKEVLE 481

  Fly   506 VQQLIKDNRRADKISAGPQSHILEGVTWDEASRLKDATVSQAGDHVVMMGAASKGIIQRGFQHNA 570
            .:..|::..|.|..:|||||.:|..|..|.:                   ..|..|::      .
Zfish   482 TRNKIREQNRQDMKTAGPQSQVLASVITDNS-------------------PPSPEIVE------P 521

  Fly   571 TVYKAPYAKNPFDNVTDDELNEYKRTVERKKKSVHGEYTDTDFSESEAVLQAGTKKYPQSEPETE 635
            .|...|...|||:.:||.||.||::.|:||:   ||:....:    |.|...|:.  |.:.|
Zfish   522 PVPPEPETPNPFNELTDHELEEYRKEVQRKQ---HGQQDGVE----EVVNDTGSS--PTTSP--- 574

  Fly   636 HQVIEIQTQQAPVPRQAEVVLSD--DDSKNNEYGDDMENQL 674
                 |:|..|...:.|:.|.:|  |:.|..|   ::|.|:
Zfish   575 -----IKTPAASDEKTADAVQNDKGDEKKKQE---ELEKQM 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hts	NP_001097377.2	Aldolase_II	116..323	CDD:238232	92/209 (44%)
add2	NP_001352363.2	None