Protein Alignment hts and add-2

DIOPT Version :9

• Sequence 1: NP_001097377.2
• Gene: hts / 37230
• FlyBaseID: FBgn0263391
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001041130.1
• Gene: add-2 / 179647
• WormBaseID: WBGene00000073
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 130/417 - (31%)
• Similarity: 216/417 - (51%)
• Gaps: 69/417 - (16%)

  Fly    14 PTAGEDDDNSKAR-----PADIEQDMREM--------ERRKRVEAIMGSKLFRE-ELERIVDSAR 64
            |...|..|..:||     .:.....:.|:        |.|:..|     :|||: ::|:..:||.
 Worm   224 PIRDEASDQKRARYSIESTSSTNNQLNEINSFVVPKFEGRQESE-----QLFRDVKVEQFEESAE 283

  Fly    65 ---DGGAGASGILQQLSDIVGVPVSRVGSVFKSSNC-------------------MVPINDIRGV 107
               :..|.:..|....:.:|..| ::....|::.:.                   :.||.|::
 Worm   284 ISINNRALSPHIQPSKTSVVNRP-NQQNRKFQNYDMFSAGVISTATVPAPMFHPHITPIADLK-- 345

  Fly   108 ESMGYAKGEKILRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALN 172
            :..||...|...|.|||:.:||:||:.|:||:...||.|:..|.:..|:|.:|.||.|::||:|.
 Worm   346 DDDGYDPEELTQRNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLI 410

  Fly   173 KVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDAC 237
            |||:.|.:::.|:||||.|::.:||||.:|..||:::|.:::....|||:|:.|.||||:::::.
 Worm   411 KVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESM 475

  Fly   238 VLGEITTHAYTG-LFDEEERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQ 301
            ::|::..|.|.| |.||.||..|||.|| :..|::|.|||.:.|||:||.|.....|::.|||||
 Worm   476 IVGDVGYHEYRGILIDEAERALLVRDLG-DRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQ 539

  Fly   302 LKLLPVGLDNLVLIPEESR-KAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSP 365
            ::.:|.|..:.|..|.:|. |.:|:               ||:...|....:.....::
 Worm   540 IRTVPGGNTDNVHFPAQSAIKQVYK---------------VASQGGGGVNRQNGHVNSM------ 583

  Fly   366 PKWRVGGAEFEALMRMLDNAGYRTGYI 392
             :|:.|..|::|.||.||..||.||.:
 Worm   584 -QWKKGELEWQAYMRQLDAQGYVTGNV 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hts	NP_001097377.2	Aldolase_II	116..323	CDD:238232	89/208 (43%)
add-2	NP_001041130.1	Aldolase_II	348..604	CDD:294146	103/278 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163350
Domainoid	1	1.000	175	1.000	Domainoid score	I2176
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5158
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001205
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100477
Panther	1	1.100	-	-	O	PTHR10672
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R22
SonicParanoid	1	1.000	-	-		X937
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.820