DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cer and CTSF

DIOPT Version :9

Sequence 1:NP_611420.1 Gene:cer / 37229 FlyBaseID:FBgn0034443 Length:79 Species:Drosophila melanogaster
Sequence 2:NP_003784.2 Gene:CTSF / 8722 HGNCID:2531 Length:484 Species:Homo sapiens


Alignment Length:83 Identity:18/83 - (21%)
Similarity:36/83 - (43%) Gaps:23/83 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 FDKNYEAEEDL-MRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLTPEEF----------- 68
            :::.||::|:. .|..::..:..|.:: .:..::|  |.:.|:...:|||.|||           
Human   194 YNRTYESKEEARWRLSVFVNNMVRAQK-IQALDRG--TAQYGVTKFSDLTEEEFRTIYLNTLLRK 255

  Fly    69 --------AQRCGKKVPP 78
                    |:..|...||
Human   256 EPGNKMKQAKSVGDLAPP 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cerNP_611420.1 Inhibitor_I29 9..68 CDD:400519 12/52 (23%)
CTSFNP_003784.2 Inhibitor_I29 187..243 CDD:214853 11/51 (22%)
Peptidase_C1 271..482 CDD:278538 2/3 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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