DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cer and ctsh

DIOPT Version :9

Sequence 1:NP_611420.1 Gene:cer / 37229 FlyBaseID:FBgn0034443 Length:79 Species:Drosophila melanogaster
Sequence 2:NP_997853.1 Gene:ctsh / 324818 ZFINID:ZDB-GENE-030131-3539 Length:330 Species:Danio rerio


Alignment Length:92 Identity:29/92 - (31%)
Similarity:46/92 - (50%) Gaps:19/92 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LVSDEEWVEYK---SKFDKNYEAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLT 64
            |.::|:...:|   |:::|.||..|...|.:|:.|:|.||::||    :|...:.||:|..:|:|
Zfish    21 LYTEEDEYHFKSWMSQYNKKYEINEFYQRLQIFLENKKRIDQHN----EGNHKFSMGLNQFSDMT 81

  Fly    65 PEEF--------AQRC----GKKVPPN 79
            ..||        .|.|    |..|..|
Zfish    82 FAEFKKTYLLTEPQNCSATRGNHVSSN 108

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cerNP_611420.1 Inhibitor_I29 9..68 CDD:400519 20/61 (33%)
ctshNP_997853.1 Inhibitor_I29 30..85 CDD:285458 20/58 (34%)
Peptidase_C1 112..327 CDD:278538
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 52 1.000 Domainoid score I11424
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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