Protein Alignment SdhA and frdA

DIOPT Version :10

• Sequence 1: NP_477210.1
• Gene: SdhA / 37228
• FlyBaseID: FBgn0261439
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_418578.1
• Gene: frdA / 948667
• ECOCYCID: EG10330
• Length: 602
• Species: Escherichia coli
• Alignment Length: 621
• Identity: 243/621 - (39%)
• Similarity: 354/621 - (57%)
• Gaps: 65/621 - (10%)

  Fly    60 DAIVVGAGGAGLRAAFGLVA--EGFRTAVITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYD 122
            |..:|||||||||||.....  ...:.|:|:|::|.||||:||:|| :||:. .:.|.:::|.:|
E. coli     7 DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGG-SAAVA-QDHDSFEYHFHD 69

  Fly   123 TVKGSDWLGDQDAIHYMTREAPKAVIELENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCC 187
            ||.|.|||.:||.:.|.....|..:.:||.:|.|:||..||.:..|.|||..::        |..
E. coli    70 TVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIE--------RTW 126

  Fly   188 AVADRTGHSLLHTLYGQSLSY-DCNYFVEYFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVI 251
            ..||:||..:||||:..||.: ....|.|:|.||::.:||..||::|:|:.:|||.:.||...|:
E. coli   127 FAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVM 191

  Fly   252 ATGGYGRAFFSCTSAHTCTGDGTAMVARQGLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLI 316
            ||||.||.:...|:....||||..|....|:|.:|:||||:||||:.|:|.|:|||||||||.|:
E. coli   192 ATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILV 256

  Fly   317 NGNGERFMERY-----APVAK------DLASRDVVSRSMTIEIMEGRG-AGPEKDHVYLQLHHLP 369
            |.||.|:::.|     .|:.:      :|..||.||::...|..:|.. :.|..|.|||.|.||.
E. coli   257 NKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLG 321

  Fly   370 PKQLAERLPGISETAMIFAGVDVTREPIPVLPTVHYNMGGVPTNYRGQVITIDKDGKDVIVPGLY 434
            .|:|.||||.|.|.|..:.|||..:|||||.||.||.|||:.|:          ...:..:.||:
E. coli   322 EKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETD----------QNCETRIKGLF 376

  Fly   435 AAGEAASSSVHGANRLGANSLLDLVVFGRACAKTIAELNKPGAPAPTLKENAGEASVANLDK--- 496
            |.||.:|..:|||||||:|||.:||||||...:...|   ..|.|....|.|.||..|.:::
E. coli   377 AVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATE---RAATAGNGNEAAIEAQAAGVEQRLK 438

  Fly   497 -LRHANGQITTADLRLKMQKTMQHHAAVFRDGPILQDGVNKMKEIYKQFKDIKVVDRSLIWNSDL 560
             |.:.:|....|.:|.:|...|:....::|...::|..::|:.|:.::||.:::.|.|.::|:||
E. coli   439 DLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDL 503

  Fly   561 VETLELQNLLANAQMTIVSAEARKESRGAHAREDFKVREDEYDFSKPLDGQQKKPMDQHWRKHTL 625
            :.|:||.:.|..|:....||.|||||||||.|.|....|.:               |.::.||||
E. coli   504 LYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERD---------------DVNFLKHTL 553

  Fly   626 SWVCNDNGDITLDYRNVIDTTLDNEVSTVPPAIRSY 661
            ::...| |...|:|.:|       :::|:|||.|.|
E. coli   554 AFRDAD-GTTRLEYSDV-------KITTLPPAKRVY 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhA	NP_477210.1	PTZ00139	49..661	CDD:240286	242/619 (39%)
frdA	NP_418578.1	PRK09231	2..583	CDD:236421	243/621 (39%)