Protein Alignment SdhA and sdha

DIOPT Version :9

• Sequence 1: NP_477210.1
• Gene: SdhA / 37228
• FlyBaseID: FBgn0261439
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001015989.1
• Gene: sdha / 548743
• XenbaseID: XB-GENE-956942
• Length: 665
• Species: Xenopus tropicalis
• Alignment Length: 641
• Identity: 493/641 - (76%)
• Similarity: 549/641 - (85%)
• Gaps: 3/641 - (0%)

  Fly    22 AAAVGVQRSYHIT-HGRQQASAANPDKISKQYPVVDHAYDAIVVGAGGAGLRAAFGLVAEGFRTA 85
            |......|::|.: :||:..||...|.||.|||||||.:||:|||||||||||||||...||.||
 Frog    27 ATCTAATRNFHFSVYGRKDTSAKLSDSISTQYPVVDHDFDAVVVGAGGAGLRAAFGLSEAGFNTA 91

  Fly    86 VITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYDTVKGSDWLGDQDAIHYMTREAPKAVIEL 150
            .|||||||||||:||||||||||||||:|||:||.||||||||||||||||||||.:||.:||||
 Frog    92 CITKLFPTRSHTVAAQGGINAALGNMEDDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVIEL 156

  Fly   151 ENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCCAVADRTGHSLLHTLYGQSLSYDCNYFVE 215
            ||||||||||:.|||||||||||||||||||||||||.|||||||||||||||:||.||.:||||
 Frog   157 ENYGMPFSRTEQGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVE 221

  Fly   216 YFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVIATGGYGRAFFSCTSAHTCTGDGTAMVARQ 280
            ||||||:.|:||||||:||.:|||::|||||||||||||||||.||||||||||||||||||.|.
 Frog   222 YFALDLLMENGECRGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTCTGDGTAMVTRA 286

  Fly   281 GLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLINGNGERFMERYAPVAKDLASRDVVSRSMT 345
            |||.|||||||||||||||||||||||||||||.|||..||||||||||||||||||||||||||
 Frog   287 GLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPVAKDLASRDVVSRSMT 351

  Fly   346 IEIMEGRGAGPEKDHVYLQLHHLPPKQLAERLPGISETAMIFAGVDVTREPIPVLPTVHYNMGGV 410
            |||.||||.|.:|||||||||||||.|||.||||||||||||||||||:|||||||||||||||:
 Frog   352 IEIREGRGCGKDKDHVYLQLHHLPPSQLASRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGI 416

  Fly   411 PTNYRGQVITIDKDGKDVIVPGLYAAGEAASSSVHGANRLGANSLLDLVVFGRACAKTIAELNKP 475
            ||||:||||| ..:|:|.:||||||.|||||:||||||||||||||||||||||||.:|||..||
 Frog   417 PTNYKGQVIT-HVNGEDRVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALSIAESCKP 480

  Fly   476 GAPAPTLKENAGEASVANLDKLRHANGQITTADLRLKMQKTMQHHAAVFRDGPILQDGVNKMKEI 540
            |.|.|::||||||.|||||||||..||...|::||:.||||||:||||||.|.:|::|..|:..|
 Frog   481 GEPVPSIKENAGEESVANLDKLRFTNGSTRTSELRINMQKTMQNHAAVFRTGSVLKEGCEKLSAI 545

  Fly   541 YKQFKDIKVVDRSLIWNSDLVETLELQNLLANAQMTIVSAEARKESRGAHAREDFKVREDEYDFS 605
            .....|||..||.::||:|||||||||||:..|..||..|||||||||||||||:|||.||||:|
 Frog   546 NSTMDDIKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYS 610

  Fly   606 KPLDGQQKKPMDQHWRKHTLSWVCNDNGDITLDYRNVIDTTLDNEVSTVPPAIRSY 661
            ||:.|||||...:||||||||:| :..|.::|:||.||||||:.:..:||||||||
 Frog   611 KPIQGQQKKSFSEHWRKHTLSYV-DGKGKVSLEYRPVIDTTLNEDCVSVPPAIRSY 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhA	NP_477210.1	PTZ00139	49..661	CDD:240286	482/611 (79%)
		NADB_Rossmann	80..469	CDD:304358	336/388 (87%)
		Succ_DH_flav_C	511..661	CDD:280980	93/149 (62%)
sdha	NP_001015989.1	PTZ00139	46..665	CDD:240286	486/620 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	714	1.000	Domainoid score	I118
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3073
Inparanoid	1	1.050	1012	1.000	Inparanoid score	I288
OMA	1	1.010	-	-		QHG60640
OrthoDB	1	1.010	-	-		D171709at33208
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	1	1.000	-	-		oto104750
Panther	1	1.100	-	-	LDO	PTHR11632
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R308
SonicParanoid	1	1.000	-	-		X1604
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110