Protein Alignment SdhA and SdhAL

DIOPT Version :9

• Sequence 1: NP_477210.1
• Gene: SdhA / 37228
• FlyBaseID: FBgn0261439
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 403/645 - (62%)
• Similarity: 505/645 - (78%)
• Gaps: 4/645 - (0%)

  Fly    21 RAAAVGVQRSYHITHGRQ--QASAANPDKISKQYPVVDHAYDAIVVGAGGAGLRAAFGLVAEGFR 83
            :.|...|.||....:|.:  |.|.........:|.::||.:||||:||||||:||.|||..:||:
  Fly     7 KRAGQHVTRSLLGPNGSRLLQVSCVRDASCKDEYSLIDHKFDAIVIGAGGAGMRAGFGLAEKGFQ 71

  Fly    84 TAVITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYDTVKGSDWLGDQDAIHYMTREAPKAVI 148
            ||:|:|||||||||:|||||:||||.||::||||:|.|||||||||||||:|||||.|||.:||.
  Fly    72 TAIISKLFPTRSHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAERAVC 136

  Fly   149 ELENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCCAVADRTGHSLLHTLYGQSLSY--DCN 211
            ||:.|||||||..|||||||.||||:|.:||||.|.|.||.||||||:|:||||||:|.:  .|:
  Fly   137 ELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSDSCH 201

  Fly   212 YFVEYFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVIATGGYGRAFFSCTSAHTCTGDGTAM 276
            |||:||.||||...|.|.|.||..|:|||.|||.|||||:|.||.||.:||.|:.|||||||.|.
  Fly   202 YFVDYFVLDLIMSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDGNAW 266

  Fly   277 VARQGLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLINGNGERFMERYAPVAKDLASRDVVS 341
            |:||.||..|:||||||||||||||||||||.|||||:.:|..||||||||||.||||||||||:
  Fly   267 VSRQELPLMDMEFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRDVVA 331

  Fly   342 RSMTIEIMEGRGAGPEKDHVYLQLHHLPPKQLAERLPGISETAMIFAGVDVTREPIPVLPTVHYN 406
            |:||:|::.|.|.||.||||:|||||:..|.:.:|||||..||.|||.||||:||:|||||||||
  Fly   332 RAMTMEVLAGNGCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTVHYN 396

  Fly   407 MGGVPTNYRGQVITIDKDGKDVIVPGLYAAGEAASSSVHGANRLGANSLLDLVVFGRACAKTIAE 471
            |||:||:|:|:|:|||::||:.:|.|||:.||.:.:||||||||||||||||::|||.||..||.
  Fly   397 MGGIPTDYKGRVVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALDIAA 461

  Fly   472 LNKPGAPAPTLKENAGEASVANLDKLRHANGQITTADLRLKMQKTMQHHAAVFRDGPILQDGVNK 536
            .|.||...|.:::.|.|.|:.|..:||.|:|.|.||.||:::|:||..||||||:|.:|::|:.|
  Fly   462 NNCPGDKPPQVEDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEGLLK 526

  Fly   537 MKEIYKQFKDIKVVDRSLIWNSDLVETLELQNLLANAQMTIVSAEARKESRGAHAREDFKVREDE 601
            :.|:.:||||||..||:::|||:|||||||||:||||...|.:.|.||||||:|||||||.|.||
  Fly   527 VAELCEQFKDIKTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTRVDE 591

  Fly   602 YDFSKPLDGQQKKPMDQHWRKHTLSWVCNDNGDITLDYRNVIDTTLDNEVSTVPPAIRSY 661
            .|:..||.||:|||.::||||||:::...:.|..::.||.|:|||||:.|:.:|||.|:|
  Fly   592 LDYGAPLAGQKKKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTLDSSVAPIPPAPRTY 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhA	NP_477210.1	PTZ00139	49..661	CDD:240286	395/613 (64%)
		NADB_Rossmann	80..469	CDD:304358	274/390 (70%)
		Succ_DH_flav_C	511..661	CDD:280980	84/149 (56%)
SdhAL	NP_648523.1	PTZ00139	37..651	CDD:240286	395/613 (64%)
		NADB_Rossmann	68..459	CDD:304358	274/390 (70%)
		Succ_DH_flav_C	502..651	CDD:280980	84/148 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454579
Domainoid	1	1.000	138	1.000	Domainoid score	I1566
eggNOG	1	0.900	-	-		E1_COG1053
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	567	1.000	Inparanoid score	I13
Isobase	1	0.950	-	0.957091	Normalized mean entropy	S148
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D171709at33208
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	1	1.000	-	-		otm51398
orthoMCL	1	0.900	-	-		OOG6_100447
Panther	1	1.100	-	-	P	PTHR11632
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1604
	12	11.750