Protein Alignment SdhA and sdha-1

DIOPT Version :10

• Sequence 1: NP_477210.1
• Gene: SdhA / 37228
• FlyBaseID: FBgn0261439
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_509446.1
• Gene: sdha-1 / 181108
• WormBaseID: WBGene00015391
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 465/648 - (71%)
• Similarity: 533/648 - (82%)
• Gaps: 7/648 - (1%)

  Fly    19 MQRAAAVGVQRSYHITHGRQQASAANPDKISK----QYPVVDHAYDAIVVGAGGAGLRAAFGLVA 79
            |.|||:.|::.:  :.......||||.....:    ||.||||||||:||||||||||||.||..
 Worm     1 MLRAASNGLRNT--VAARSVSLSAANHSDAKRSDIAQYKVVDHAYDAVVVGAGGAGLRAAMGLAE 63

  Fly    80 EGFRTAVITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYDTVKGSDWLGDQDAIHYMTREAP 144
            .|.:||||||||||||||:|||||||||||||..|:|:||.|||||||||||||||||||||||.
 Worm    64 GGLKTAVITKLFPTRSHTVAAQGGINAALGNMNPDNWRWHFYDTVKGSDWLGDQDAIHYMTREAE 128

  Fly   145 KAVIELENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCCAVADRTGHSLLHTLYGQSLSYD 209
            :|||||||||||||||.|||||||||||||..||:||||||.|.|||||||||||||||.||.|:
 Worm   129 RAVIELENYGMPFSRTTDGKIYQRAFGGQSNDFGRGGQAHRTCCVADRTGHSLLHTLYGASLQYN 193

  Fly   210 CNYFVEYFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVIATGGYGRAFFSCTSAHTCTGDGT 274
            |||||||||||||.|:|.|.||:|::|||||:||||:||||:|||||||||||||||||||||||
 Worm   194 CNYFVEYFALDLIMENGVCVGVIAMDLEDGTIHRFRSKNTVLATGGYGRAFFSCTSAHTCTGDGT 258

  Fly   275 AMVARQGLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLINGNGERFMERYAPVAKDLASRDV 339
            |:.||.|:.:.|:||||||||||||||||||||.|||||||:|..||||||||||.|||||||||
 Worm   259 ALTARAGINNSDMEFVQFHPTGIYGAGCLITEGSRGEGGYLVNSAGERFMERYAPNAKDLASRDV 323

  Fly   340 VSRSMTIEIMEGRGAGPEKDHVYLQLHHLPPKQLAERLPGISETAMIFAGVDVTREPIPVLPTVH 404
            ||||||:|||||||.||:|||:||||||||.:||.:||||||||||||||||||:|||||:||||
 Worm   324 VSRSMTVEIMEGRGVGPDKDHIYLQLHHLPAEQLQQRLPGISETAMIFAGVDVTKEPIPVIPTVH 388

  Fly   405 YNMGGVPTNYRGQVITIDKDGKDVIVPGLYAAGEAASSSVHGANRLGANSLLDLVVFGRACAKTI 469
            ||||||||||:|||:.......|.:|||||||||..:.|||||||||||||||||:||||||..|
 Worm   389 YNMGGVPTNYKGQVLNYTPKKGDEVVPGLYAAGECGAHSVHGANRLGANSLLDLVIFGRACAIDI 453

  Fly   470 AELNKPGAPAPTLKENAGEASVANLDKLRHANGQITTADLRLKMQKTMQHHAAVFRDGPILQDGV 534
            .:....|...|.|.:|||||||||:|||||..|.|:||:|||.|||:||:||||||.|.||::||
 Worm   454 LKNTSAGVGVPELPKNAGEASVANIDKLRHNKGDISTAELRLTMQKSMQNHAAVFRRGDILKEGV 518

  Fly   535 NKMKEIYKQFKDIKVVDRSLIWNSDLVETLELQNLLANAQMTIVSAEARKESRGAHAREDFKVRE 599
            ..:.::||....:.|.|:.|:|||||:|||||||||.||..|||:||.|:||||||||:||..|.
 Worm   519 KVLSKLYKDQAHLNVADKGLVWNSDLIETLELQNLLINATQTIVAAENREESRGAHARDDFPDRL 583

  Fly   600 DEYDFSKPLDGQQKKPMDQHWRKHTLSWVCNDNGDITLDYRNVIDTTLD-NEVSTVPPAIRSY 661
            ||.|:||||:||.||.:..|||||::.....:.|:::||||.||||||| :|...|||.:|||
 Worm   584 DELDYSKPLEGQTKKELKDHWRKHSIIRSNIETGEVSLDYRPVIDTTLDKSETDWVPPKVRSY 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhA	NP_477210.1	PTZ00139	49..661	CDD:240286	454/616 (74%)
sdha-1	NP_509446.1	FAD_binding_2	36..646	CDD:481218	453/609 (74%)