Protein Alignment SdhA and Sdha

DIOPT Version :9

• Sequence 1: NP_477210.1
• Gene: SdhA / 37228
• FlyBaseID: FBgn0261439
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_569112.1
• Gene: Sdha / 157074
• RGDID: 621557
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 490/663 - (73%)
• Similarity: 557/663 - (84%)
• Gaps: 9/663 - (1%)

  Fly     1 MSGIMRVPSILAKNAVASMQRAAAVGVQRSYHITHGR-QQASAANPDKISKQYPVVDHAYDAIVV 64
            |:|:..|..:|..      :|.|..|..|.:|.:.|. ::|||...|.||.|||||||.:||:||
  Rat     1 MAGVGAVSRLLRG------RRLALAGATRGFHFSVGESKKASAKVSDAISTQYPVVDHEFDAVVV 59

  Fly    65 GAGGAGLRAAFGLVAEGFRTAVITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYDTVKGSDW 129
            |||||||||||||...||.||.:||||||||||:||||||||||||||||:|:||.|||||||||
  Rat    60 GAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDW 124

  Fly   130 LGDQDAIHYMTREAPKAVIELENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCCAVADRTG 194
            |||||||||||.:||.:|:||||||||||||:||:|||||||||||||||||||||||.||||||
  Rat   125 LGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGKGGQAHRCCCVADRTG 189

  Fly   195 HSLLHTLYGQSLSYDCNYFVEYFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVIATGGYGRA 259
            |||||||||:||.||.:||||||||||:.|:||||||:||.:|||::||.|||||:||||||||.
  Rat   190 HSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTIIATGGYGRT 254

  Fly   260 FFSCTSAHTCTGDGTAMVARQGLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLINGNGERFM 324
            :||||||||.||||||||.|.|||.|||||||||||||||||||||||||||||.|||..|||||
  Rat   255 YFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFM 319

  Fly   325 ERYAPVAKDLASRDVVSRSMTIEIMEGRGAGPEKDHVYLQLHHLPPKQLAERLPGISETAMIFAG 389
            |||||||||||||||||||||:||.||||.||||||||||||||||:|||.||||||||||||||
  Rat   320 ERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAG 384

  Fly   390 VDVTREPIPVLPTVHYNMGGVPTNYRGQVITIDKDGKDVIVPGLYAAGEAASSSVHGANRLGANS 454
            ||||:|||||||||||||||:||||:|||:. ..:|:|.|||||||.||||.:||||||||||||
  Rat   385 VDVTKEPIPVLPTVHYNMGGIPTNYKGQVLK-HVNGQDQIVPGLYACGEAACASVHGANRLGANS 448

  Fly   455 LLDLVVFGRACAKTIAELNKPGAPAPTLKENAGEASVANLDKLRHANGQITTADLRLKMQKTMQH 519
            ||||||||||||.:|||..:||...|.:|.||||.||.||||||.|:|.:.|::|||.|||:||.
  Rat   449 LLDLVVFGRACALSIAESCRPGDKVPPIKANAGEESVMNLDKLRFADGSVRTSELRLSMQKSMQS 513

  Fly   520 HAAVFRDGPILQDGVNKMKEIYKQFKDIKVVDRSLIWNSDLVETLELQNLLANAQMTIVSAEARK 584
            ||||||.|.:||:|..|:.::|...:.:|..||.::||:|||||||||||:..|..||..|||||
  Rat   514 HAAVFRVGSVLQEGCEKVSQLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARK 578

  Fly   585 ESRGAHAREDFKVREDEYDFSKPLDGQQKKPMDQHWRKHTLSWVCNDNGDITLDYRNVIDTTLDN 649
            ||||||||||:|||.||||:|||::||||||..:||||||||:|....|.:|||||.|||.||:.
  Rat   579 ESRGAHAREDYKVRIDEYDYSKPIEGQQKKPFAEHWRKHTLSYVDTKTGKVTLDYRPVIDKTLNE 643

  Fly   650 -EVSTVPPAIRSY 661
             :.:|||||||||
  Rat   644 ADCATVPPAIRSY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhA	NP_477210.1	PTZ00139	49..661	CDD:240286	473/612 (77%)
		NADB_Rossmann	80..469	CDD:304358	329/388 (85%)
		Succ_DH_flav_C	511..661	CDD:280980	95/150 (63%)
Sdha	NP_569112.1	PTZ00139	44..656	CDD:240286	473/612 (77%)
		NADB_Rossmann	77..463	CDD:304358	328/386 (85%)
		Succ_DH_flav_C	507..656	CDD:280980	94/148 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343952
Domainoid	1	1.000	703	1.000	Domainoid score	I116
eggNOG	1	0.900	-	-		E1_COG1053
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3073
Inparanoid	1	1.050	1001	1.000	Inparanoid score	I281
OMA	1	1.010	-	-		QHG60640
OrthoDB	1	1.010	-	-		D171709at33208
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	1	1.000	-	-		oto98061
orthoMCL	1	0.900	-	-		OOG6_100447
Panther	1	1.100	-	-	LDO	PTHR11632
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1604
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810