DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10081 and Naaladl1

DIOPT Version :9

Sequence 1:	NP_611418.1	Gene:	CG10081 / 37226	FlyBaseID:	FBgn0034441	Length:	875	Species:	Drosophila melanogaster
Sequence 2:	NP_113947.1	Gene:	Naaladl1 / 83568	RGDID:	620987	Length:	745	Species:	Rattus norvegicus

Alignment Length:	412	Identity:	88/412 - (21%)
Similarity:	152/412 - (36%)	Gaps:	110/412 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 NLYDFEAIGTKVVGSDENEHKTVQFLLKELNLIKDNIQEDLFDMEIDLQYAYGAYVKWN------ 141
            |:..|..|.|:.:|.::.::     ||..||   .....|.:...:..:|..|...:.|
  Rat   279 NISGFPPIPTQPIGFEDAKN-----LLCNLN---GTSAPDSWQGALGCEYKLGPGFEPNGNFPAG 335

  Fly   142 ---LVNMYQGIQ----NVVVKLTPKGTTSENYILVNSHFDS---QPTSPSTGDDGHMVVSILEVL 196
               .|::|..::    :.|:.:.......:.|::..:|.||   ....||:|     ...:||:.
  Rat   336 SEVKVSVYNRLELRNSSNVLGIIQGAVEPDRYVIYGNHRDSWVHGAVDPSSG-----TAVLLEIS 395

  Fly   197 RVISS-RRKSFEHP---IIFLINGSEENSLQASHGFIA--YHKWAKNCKAVINLDAAGSGGRELM 255
            ||:.: .:|....|   |||...|:||..|..|..|..  ..|..:.....||:|.:......|.
  Rat   396 RVLGTLLKKGTWRPRRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVTYINVDISVFSNATLR 460

  Fly   256 FQ----------------SGPNNPWLVKIYKDGAKHYFSTTMAEEIFQTGLVPSY------TDFD 298
            .|                |.|.:..| .||.:..::   |..:..::  |||||.      :|:.
  Rat   461 AQGTPPVQSVIFSATKEISAPGSSGL-SIYDNWIRY---TNRSSPVY--GLVPSMGTLGAGSDYA 519

  Fly   299 IFVEYGNLIGLDIGQCINGF--------VYHTKYDRIDVIPR----------AALQNTGDNLLGL 345
            .|:.:..:..:|:....:..        .|||.:|..|.:.:          |..:..|..||.|
  Rat   520 SFIHFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRL 584

  Fly   346 VQTL------SNASE-----LRDLSANPTGNTIFFDVLGLYLISYSADVGVKL----NYAVAAAA 395
            ..:|      |:.||     |:....|          ||..|.|::..:|..:    .:..||||
  Rat   585 SDSLFLPLNVSDYSETLQSFLQAAQEN----------LGALLESHNISLGPLVTAVEKFKAAAAA 639

  Fly   396 IILIYISLLRIAEKSSVSSEQI 417
            :....::|    :|||....|:
  Rat   640 LNQHILTL----QKSSPDPLQV 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:193497	77/368 (21%)
Naaladl1	NP_113947.1	Zinc_peptidase_like	53..>126	CDD:387401
		PA_GCPII_like	119..331	CDD:239036	13/59 (22%)
		M28_PSMA_like	<353..592	CDD:349942	54/249 (22%)
		TFR_dimer	621..740	CDD:367885	10/41 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900