Sequence 1: | NP_611418.1 | Gene: | CG10081 / 37226 | FlyBaseID: | FBgn0034441 | Length: | 875 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001121620.1 | Gene: | TFRC / 7037 | HGNCID: | 11763 | Length: | 760 | Species: | Homo sapiens |
Alignment Length: | 893 | Identity: | 152/893 - (17%) |
---|---|---|---|
Similarity: | 272/893 - (30%) | Gaps: | 364/893 - (40%) |
- Green bases have known domain annotations that are detailed below.
Fly 173 FDSQPTSPS--------TGDDGH--MVVSILEVLRVISSRRKSFEHP--------------IIFL 213
Fly 214 INGSEENSLQASHGFIAYHKWAKNCKAVINLDAAGSGGRELMFQSGPNNPWLVKIYKDGAKHYFS 278
Fly 279 TTMAEEIFQTGLVPSYTDFDIFVEYGNLIGLDIGQCINGFVYHTKYDRIDVIPRAALQNTGDNLL 343
Fly 344 GLVQT------LSNA--------SELRDLSANPTGNTIFFDVLG--LYL-------ISYS----- 380
Fly 381 ------ADVGVKLN----YAVAAAAIILIYISLLRIAEKSSVSSEQILSTFILVLVVQLIAFVLA 435
Fly 436 LALPLLVAYGLDKYGLSLSYFATPSLLIGLYICPSLLGLTLPSYIYLK--------LANTEKVSF 492
Fly 493 AQQVQLALHGHAAVLSILCIAINYYGLRTTYVITWTLAFYVIPLAFNLLTTLHDRGYSWTGILKI 557
Fly 558 VQVAPFMYNSYLFYCFIVILTPMMGRFGV---DTNPD--LIIG----------ALTALGTILSMG 607
Fly 608 FLILLVNMSRRSGFVLIGLLAVTAAGVYIASSTDIGFPYRPKTNVQRVPYLQVRRIFYEYD---- 668
Fly 669 GTVSKDE--SGYLFNLQ---------DRRGL---------TPLLESNVDLTGLVNMTSDCAKYMM 713
Fly 714 CGMPLY-DHRWVEAME----------------------------------TTM--------WLPR 735
Fly 736 KNPVWTPAEPI-------------------------------LKQLNKTVLADGQTVQFEF---- 765
Fly 766 -------ELTT----SDHTSIFISP--NEDVIISNWSFLKEYLTTNSPPY-HIYYSFG------- 809
Fly 810 IDNTPLRFHIELKKADGVYTVPLFQMGIGAHYMHVKGDDESIRLANSL 857 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG10081 | NP_611418.1 | M28_Fxna_like | 72..379 | CDD:193497 | 45/252 (18%) |
TFRC | NP_001121620.1 | Mediates interaction with SH3BP4. /evidence=ECO:0000269|PubMed:16325581 | 1..67 | 9/53 (17%) | |
Endocytosis signal. /evidence=ECO:0000269|PubMed:2298808 | 20..23 | 0/2 (0%) | |||
Stop-transfer sequence. /evidence=ECO:0000303|PubMed:6090955 | 58..61 | 1/2 (50%) | |||
PA_TfR | 201..377 | CDD:239043 | 37/208 (18%) | ||
M28_TfR | 385..610 | CDD:193572 | 44/285 (15%) | ||
Ligand-binding | 569..760 | 34/192 (18%) | |||
TFR_dimer | 642..750 | CDD:282153 | 24/119 (20%) | ||
Cell attachment site, required for binding to transferrin | 646..648 | 0/1 (0%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG2234 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |