DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10081 and Tfr2

DIOPT Version :9

Sequence 1:	NP_611418.1	Gene:	CG10081 / 37226	FlyBaseID:	FBgn0034441	Length:	875	Species:	Drosophila melanogaster
Sequence 2:	XP_030110515.1	Gene:	Tfr2 / 50765	MGIID:	1354956	Length:	840	Species:	Mus musculus

Alignment Length:	326	Identity:	61/326 - (18%)
Similarity:	125/326 - (38%)	Gaps:	84/326 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 ENYILVNSHFDSQPTSPSTGDDGHMVVSILEVLRVISSRRKSFEHP---IIFLI-NGSEENSLQA 224
            ::|:::.:..|:  ..|...........:||::|..||...:...|   ::|:. :|.:..|:.|
Mouse   461 DHYVVIGAQRDA--WGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGA 523

  Fly   225 SHGFIAYHKWAKNCKAVINLDAA----------GSGGRELMFQSGPNNPWLVKIYKDGAK----- 274
            :       :|.:...:|::|.|.          |.|    .|.: ..:|.||.:.::..|
Mouse   524 T-------EWLEGYLSVLHLKAVVYVSLDNSVLGDG----KFHA-KTSPLLVSLIENILKQVDSP 576

  Fly   275 HYFSTTMAEEIFQTGLVPSYTDFDI------------FVEYGNLIGLDIGQCINGFVY---HTKY 324
            ::...|:.|::..|.  ||: |.::            |..:..:..::.....:..||   |||.
Mouse   577 NHSGQTLYEQVALTH--PSW-DAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTKE 638

  Fly   325 D-----------RIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSANPTGNTIFFDVLGLYLIS 378
            |           |:..:.:|..|..|..|:.|     :...|..|.....|:.:...:..|.  .
Mouse   639 DTYENLHKMLRGRLPAVVQAVAQLAGQLLIRL-----SHDHLLPLDFGRYGDVVLRHIGNLN--E 696

  Fly   379 YSADV---GVKLNYAVAAAAIILIYISLLRIAEK------SSVSSEQILSTFILVLVVQLIAFVL 434
            :|.|:   |:.|.:..:|..      ..:|.|||      ||..:::.|.....|.::::..:.|
Mouse   697 FSGDLKERGLTLQWVYSARG------DYIRAAEKLRKEIYSSERNDERLMRMYNVRIMRVEFYFL 755

  Fly   435 A 435
            :
Mouse   756 S 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:193497	47/259 (18%)
Tfr2	XP_030110515.1	PA_TfR	248..438	CDD:239043
		M28_TfR	446..679	CDD:349946	44/239 (18%)
		TFR_dimer	706..830	CDD:367885	11/57 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900