Protein Alignment CG10081 and Ermp1

DIOPT Version :10

• Sequence 1: NP_611418.1
• Gene: CG10081 / 37226
• FlyBaseID: FBgn0034441
• Length: 875
• Species: Drosophila melanogaster
• Sequence 2: XP_006231303.1
• Gene: Ermp1 / 373544
• RGDID: 727831
• Length: 899
• Species: Rattus norvegicus
• Alignment Length: 896
• Identity: 270/896 - (30%)
• Similarity: 435/896 - (48%)
• Gaps: 138/896 - (15%)

  Fly    49 LFIAVVKPLFYRLPEPLTVEDAS--KGGFIAERAQANLYDFEAIGTKVVGSDENEHKTVQFLLKE 111
            |::..::.|.....:.|.:...|  :|.|.|.:|:..|....|||.:..||.|||..|||:||::
  Rat    73 LYLLALRALVQLSLQRLVLSRTSGLQGEFDARQARVYLEHITAIGPRTTGSAENEILTVQYLLEQ 137

  Fly   112 LNLIKDNIQEDLFDMEIDLQYAYGAY---VKWNLVNMYQGIQNVVVKLTPKGTTSENYILVNSHF 173
            :.||::. ...|..:.:|:|...|::   ......:.|..|.||||||.|: ..::..:|.|.||
  Rat   138 ITLIEEQ-SNSLHRISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPQ-DGAKYAVLANCHF 200

  Fly   174 DSQPTSPSTGDDGHMVVSILEVLRVISSRRKSFEHPIIFLINGSEENSLQASHGFIAYHKWAKNC 238
            ||...||...||......:||||||:::..:..:|.::||.||:|||.||||||||..|.||...
  Rat   201 DSVANSPGASDDAVSCAVMLEVLRVMAASPEPLQHAVVFLFNGAEENVLQASHGFITQHPWASLI 265

  Fly   239 KAVINLDAAGSGGRELMFQSGPNNPWLVKIYKDGAKHYFSTTMAEEIFQTGLVPSYTDFDIFVEY 303
            :|.|||:|||.||:||:||:||.|||||:.|...|||.|::.:|:|:||:|::||.|||.|:.::
  Rat   266 RAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDF 330

  Fly   304 GNLIGLDIGQCINGFVYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSANPTGNTIF 368
            ||:.|:|:....||::||||||..|.|...::|..|||:|.:::.|:.:..|...|....|:.:|
  Rat   331 GNIPGIDLAFIENGYIYHTKYDTADRILIDSIQRAGDNILAVLKYLATSDMLASSSEYRHGSMVF 395

  Fly   369 FDVLGLYLISYSADVGVKLNYAVAAAAIILIYISLLRIAEKSSVSSEQILSTFILVLVVQLIAFV 433
            ||||||.:|:|.:.||..:||.|..|.::.:...|||...::|    ..:..|:..|.:..|::.
  Rat   396 FDVLGLLVIAYPSRVGSIINYMVVMAVVLYLGRKLLRPKHRNS----NYVRDFLCGLGITFISWF 456

  Fly   434 LALALPLLVAYGLDKYGLSLSYFATPSLLIGLYICPSLLGLTLPSYIYLKLANTEKVSFAQQVQL 498
            .:|...|::|..:...|.|||::                     :|.|              :.:
  Rat   457 TSLVTVLIIAVFVSLIGQSLSWY---------------------NYFY--------------IAV 486

  Fly   499 ALHGHAAVLSILCI---AINYYGLRTTYVITWTLAF---------YVIPL--------------- 536
            .|:|.|.|..|:.|   |..:|.:..:.:....|.|         :::.|
  Rat   487 CLYGTATVAKIILIHTLAKRFYYVNASDLYLGELFFDTSLFVHCGFLVALTAQGFCSAFMSAVWV 551

  Fly   537 AFNLLTTL--------HDRGYSWTGILKIVQVAPFMYNSYLFYCFIVILTPMMGRFGVDTNPDLI 593
            ||.|||.|        |.....:..:..:....|::|..||.:....:.||::||.|.:..||::
  Rat   552 AFPLLTKLCVYKDFKKHGAKGRFIALYLLGMFIPYLYGLYLIWAVFEMFTPILGRSGSEIPPDVV 616

  Fly   594 IGALTALGT-ILSMGFL--ILLVNMSRRSGFVLIGLLAVT----AAGVYIASSTDIGFPYRPKTN 651
            :.::.|:.. |||..|:  |.|||.::::...||.:.|||    .:|.:...|::   |..||.
  Rat   617 LASILAVCVMILSSYFITFIYLVNSTKKTILTLILVCAVTFLLVCSGAFFPYSSN---PDSPKP- 677

  Fly   652 VQRVPYLQVRRIFYEYDGTVSKDESGYLFNLQDRRGL---TPLLESNVDLTGLVNMTSDCAKYM- 712
             :||....|.|.|:..:|:|.|.:||...|..|..|:   ||.:....|     .:.:.|.:..
  Rat   678 -KRVFLQHVSRTFHNLEGSVVKRDSGIWINGFDYTGMSHVTPHIPEIND-----TIRAHCEENAP 736

  Fly   713 MCGMPLYDHRWVEAMETTMWLP-----RKN-----PVWTPAEPILKQLNKTVLADGQTVQFEFEL 767
            :||.|.|             ||     |||     |..:|..|...:|.........:::..||.
  Rat   737 LCGFPWY-------------LPVHFLIRKNWYLPAPEISPRNPAHFRLVSKEKMPWDSIKLTFEA 788

  Fly   768 TTSDHTSIFISPNEDVIISNWSFLKEY-LTTNSPPYHIYYSFGIDNTPLRFHIELKKA-----DG 826
            |...|.|.::..::...:|.||..... :|:....|.::||.|:..:..:|.||:::.     :|
  Rat   789 TGPSHMSFYVRTHKGSTLSQWSLGNGIPVTSRGGDYFVFYSHGLQASAWQFWIEVQQVSEEQPEG 853

  Fly   827 VYTVPLFQMGIGAHYM--HVKGDDESIRLANSLPDYAVSIQWPAMYKKYIF 875
            :.||     .|.|||:  ..|...:...|....||::....|.:.|..::|
  Rat   854 MVTV-----AIAAHYLSGENKRSSQLDALKEKFPDWSFPSAWVSTYSLFVF 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:349872	135/309 (44%)
Ermp1	XP_006231303.1	M28_Fxna_like	99..406	CDD:349872	135/308 (44%)