DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10081 and Naalad2

DIOPT Version :9

Sequence 1:	NP_611418.1	Gene:	CG10081 / 37226	FlyBaseID:	FBgn0034441	Length:	875	Species:	Drosophila melanogaster
Sequence 2:	NP_001100272.1	Gene:	Naalad2 / 300384	RGDID:	1305872	Length:	778	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	91/429 - (21%)
Similarity:	151/429 - (35%)	Gaps:	125/429 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 YFAGGIVLF---WALLFIAVVKPLFYRL---PEPLTVEDASKGGFIAERAQANLYDFEAIGTKVV 95
            |||.|:..:   |.|...|..:.....|   .:|||      .|:.|:.....|...||:|...:
  Rat   262 YFAPGVQPYPKGWNLPGAAAQRGNVLNLNGAGDPLT------PGYPAKEYTFRLPVEEAVGIPNI 320

  Fly    96 GSDENEHKTVQFLLKELNLIKDNIQEDLFDMEIDLQY---------AYGAYVKWNL--VNMYQGI 149
            ......:...:.||:  ||......:..:...:::.|         .|...|:.::  :|....|
  Rat   321 PVHPIGYNDAERLLR--NLGGTAPPDQSWKGSLNVSYNIGPGFSGSEYSRKVRMHVHNINKITRI 383

  Fly   150 QNVVVKLTPKGTTS-ENYILVNSHFDS---QPTSPSTGDDGHMVVSILEVLRVISSRRKSF---- 206
            .||:.  |.:|:|. :.|:::..|.||   ....|:||         ..||:.|:   :||
  Rat   384 YNVIG--TIRGSTEPDRYVILGGHRDSWVFGGIDPTTG---------TAVLQEIA---RSFGKLV 434

  Fly   207 ------EHPIIFLINGSEENSLQASHGFIAYHKWA-KNCK-------AVINLDAAGSGGRELMFQ 257
                  ...|||....:||      .|.:...:|| :|.|       |.||.|:|..|...|...
  Rat   435 NGGWKPRRTIIFASWDAEE------FGLLGSTEWAEENAKILQERSIAYINSDSAIEGNYTLRVD 493

  Fly   258 SGPNNPWLVKIYK---------DGAKHYFSTTMAEEIFQTGLVP------------SYTDFDIFV 301
            ..|....||  ||         ||   :.|.::.|...:....|            |.:||:
  Rat   494 CTPLLHQLV--YKVAREISSPDDG---FESKSLYESWLEKDPSPENKERPRINKLGSGSDFE--- 550

  Fly   302 EYGNLIGLDIGQC----------INGF-VYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASEL 355
            .|...:|:..|:.          .:.: ||||.|:..:                |||...:.:..
  Rat   551 AYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFE----------------LVQNFYDPTFK 599

  Fly   356 RDLSANPTGNTIFFDVLGLYLISYSADVGVKL--NYAVA 392
            :.||.......:.:::....:|.::.....|.  |||.:
  Rat   600 KQLSVAQLRGALVYELADCVVIPFNIQDYAKALKNYAAS 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:193497	76/371 (20%)
Naalad2	NP_001100272.1	Zinc_peptidase_like	86..>143	CDD:417508
		PA_GCPII_like	148..374	CDD:239036	24/119 (20%)
		M28_PSMA_like	<382..623	CDD:349942	62/284 (22%)
		TFR_dimer	655..774	CDD:398094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900