Protein Alignment CG10081 and C44B7.11

DIOPT Version :10

• Sequence 1: NP_611418.1
• Gene: CG10081 / 37226
• FlyBaseID: FBgn0034441
• Length: 875
• Species: Drosophila melanogaster
• Sequence 2: NP_495410.4
• Gene: C44B7.11 / 183431
• WormBaseID: WBGene00016631
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 967
• Identity: 261/967 - (26%)
• Similarity: 430/967 - (44%)
• Gaps: 178/967 - (18%)

  Fly     3 DKEKLILDDHVEEGVKSYSRKHGRKHRVYFQLP--WYFAGGIVLFWALLFIAVVKPLFYRLPEPL 65
            |::|.||:   :|.:::...:...:..:....|  |.|.|   ||:.:|.|.... |...||||.
 Worm    11 DEKKNILE---KESLQNDETQREMEKDISLLRPAHWNFIG---LFFLVLIIGTTF-LHKCLPEPK 68

  Fly    66 TVEDASKGGFIAERAQANLYDFEAIGTKVVGSDENEHKTVQFLLKELNLIK---DNIQEDLFDME 127
            . .:..:..|..:||...|.:....|.|..||...|..|...:|||||.|:   .|::...||
 Worm    69 D-PNQEETQFSEKRAVKVLQELSDYGWKPAGSYNCEELTRNRILKELNDIRSQNQNVENLRFD-- 130

  Fly   128 IDLQYAYG-----AYVKWNLVNMYQGIQNVVVKLTPKGTTSENY-ILVNSHFDSQPTSPSTGDDG 186
            ||.||..|     |:....:...|:.:.||:.:| .||...:.. :|:|.|:||.|||.:..||.
 Worm   131 IDTQYVSGCFDIPAHDTEGMNICYRNVSNVMARL-GKGEKKDKISVLLNCHYDSWPTSNAGSDDL 194

  Fly   187 HMVVSILEVLRVISSRRKSFEHPIIFLINGSEENSLQASHGFIAYHKWAKNCKAVINLDAAGSGG 251
            .....:||::|:.|.......|.:|||.||:||:||.|:||||..|.|....:|.|||:|:||||
 Worm   195 SSCALMLELIRLYSKNPHLLNHDVIFLFNGAEESSLLAAHGFITQHSWRHEIRAFINLEASGSGG 259

  Fly   252 RELMFQSGPNNPWLVKIYKDGAKHYFSTTMAEEIFQTGLVPSYTDFDIFVEYGNLIGLDIGQCIN 316
            |||:||:||.|.||:..|.:.|.|...:.:.:|:||:|:.|..|||.||.::|.:.|||:....|
 Worm   260 RELLFQAGPANQWLLNSYLEAAIHPHCSVIGQEVFQSGVYPGDTDFRIFRDHGRVPGLDLAFVQN 324

  Fly   317 GFVYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSANPTGNTIFFDVLGLYLISYSA 381
            |:.:||::|..:.|.:.:||..|:|:...:..|..:..|...:......|:|||.|||::|.|..
 Worm   325 GYWWHTEFDTAERITKGSLQRAGENVYSTLNHLLKSPYLEKPAEYADRKTVFFDFLGLFVIIYPL 389

  Fly   382 DVGVKLNYAVAAAAIILIYISLLRIAEKSSVSSEQILS-TFILVLVVQ---LIAFVLALALPLLV 442
            .:...:|              :|.|....::.|.:..| |||..|.::   |....:||.|..:.
 Worm   390 SIAHLVN--------------MLTICTVIALMSHRFYSKTFITFLALRDYVLTILTIALVLKAMT 440

  Fly   443 AYGLDKYGLSLSYFATPSLLIGLYICPSL-LGLTLPSYIYLKLANTEKVSFAQQVQLALHGHAAV 506
            ...|..|| :|.::....|.:..|..||: .|:::...:..:||...:..:...::|.   |..:
 Worm   441 FMSLFTYG-ALRWYTRHWLALVAYGLPSVWAGISVQGLLTARLAPKAREEYGSTLELI---HLTL 501

  Fly   507 LSILCIAINYYGLRTTY------------VITWTLAFYVIPLAFNLLTTLHDRGYSWTGILKIVQ 559
            :|.:.:|..||.:.:.:            :||:..|:...| .||.:.||         ||....
 Worm   502 ISGILLAFTYYDIASGFLFALLLVPAIKSIITYFGAWPTCP-TFNTILTL---------ILSFPG 556

  Fly   560 VAPFMYNSYLFYCFIVILTPMMGRFGVDTNPDLIIGALTALGT---ILSMGFLILLVNMSRRSG- 620
            .|..:|.:.:   .:.|..|:|||...  ||:..:....|...   :||:|.|:.....||.|.
 Worm   557 CAMAIYTTEM---LLSIFIPIMGRSSY--NPEPAVSFFVAFSAGCIVLSLGGLVAKSRNSRSSNE 616

  Fly   621 -------FVLIGLLAVTAAGVYIASSTDIGF---PYR-----PKTNVQRVPYLQVRRIFYEYDGT 670
                   :.::|:|.||...:|:.||    |   |||     |  ..:|..:..|.::.|:.:|.
 Worm   617 AGLLELIYNILGVLLVTLTILYVFSS----FWPSPYRFDNVYP--TAKRTQFFHVNQMLYDRNGQ 675

  Fly   671 VSKDESGYLFNLQDRRGL--TPLLESNVDLTGLVNMTSDCAKYMMCGMPLYDHR-WVEAMETTMW 732
            :|.:::.:.....|.||.  .|.::.:.:.|||           .|.   |::. |.|
 Worm   676 ISVNDTRFYAISHDYRGAEDIPFVKKDPEYTGL-----------QCH---YENNPWCE------- 719

  Fly   733 LPRKNPVWTPAEPILKQLNKTVLA-------------------------DGQ-TVQFEFELTTSD 771
                .|...|.:..|.:.|..|.:                         ||: .:::.|.:..:.
 Worm   720 ----TPFLFPTKGRLNERNIRVRSVDERLKFKHPVKILGISKRHGVDSKDGKGNIEYSFSVIGTG 780

  Fly   772 HTSIFISPNEDVIISNWSFLKEYLTTNSPPYH---IYYSFGIDNT--PLRFHIELKKADGVYT-- 829
            ..|::|.|:...:|:|.|     :|....|..   :||:....|.  ...|.:.:||.....:
 Worm   781 QISVYIIPDTTWLITNTS-----VTQPKTPQENMFLYYTCSTPNNICEWMFKVTIKKTTQTPSDD 840

  Fly   830 VPLFQMGIGAHYMH-VKGDDESIR---------LANSLPDYAVSIQ-W--PAMYKKY 873
            .||. :||.:||:| .:...|||:         ..|| |::.|:.. |  ..:||.:
 Worm   841 KPLL-IGISSHYLHGPEMQSESIKNMIAKIQENRVNS-PEWTVTASAWNVDQVYKYF 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:349872	118/315 (37%)
C44B7.11	NP_495410.4	M28_Fxna_like	75..387	CDD:349872	118/314 (38%)
		COG5373	<444..>646	CDD:444140	52/224 (23%)