Protein Alignment CG10081 and C44B7.11

DIOPT Version :9

• Sequence 1: NP_611418.1
• Gene: CG10081 / 37226
• FlyBaseID: FBgn0034441
• Length: 875
• Species: Drosophila melanogaster
• Sequence 2: NP_495410.4
• Gene: C44B7.11 / 183431
• WormBaseID: WBGene00016631
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 967
• Identity: 261/967 - (26%)
• Similarity: 430/967 - (44%)
• Gaps: 178/967 - (18%)

  Fly     3 DKEKLILDDHVEEGVKSYSRKHGRKHRVYFQLP--WYFAGGIVLFWALLFIAVVKPLFYRLPEPL 65
            |::|.||:   :|.:::...:...:..:....|  |.|.|   ||:.:|.|.... |...||||.
 Worm    11 DEKKNILE---KESLQNDETQREMEKDISLLRPAHWNFIG---LFFLVLIIGTTF-LHKCLPEPK 68

  Fly    66 TVEDASKGGFIAERAQANLYDFEAIGTKVVGSDENEHKTVQFLLKELNLIK---DNIQEDLFDME 127
            . .:..:..|..:||...|.:....|.|..||...|..|...:|||||.|:   .|::...||
 Worm    69 D-PNQEETQFSEKRAVKVLQELSDYGWKPAGSYNCEELTRNRILKELNDIRSQNQNVENLRFD-- 130

  Fly   128 IDLQYAYG-----AYVKWNLVNMYQGIQNVVVKLTPKGTTSENY-ILVNSHFDSQPTSPSTGDDG 186
            ||.||..|     |:....:...|:.:.||:.:| .||...:.. :|:|.|:||.|||.:..||.
 Worm   131 IDTQYVSGCFDIPAHDTEGMNICYRNVSNVMARL-GKGEKKDKISVLLNCHYDSWPTSNAGSDDL 194

  Fly   187 HMVVSILEVLRVISSRRKSFEHPIIFLINGSEENSLQASHGFIAYHKWAKNCKAVINLDAAGSGG 251
            .....:||::|:.|.......|.:|||.||:||:||.|:||||..|.|....:|.|||:|:||||
 Worm   195 SSCALMLELIRLYSKNPHLLNHDVIFLFNGAEESSLLAAHGFITQHSWRHEIRAFINLEASGSGG 259

  Fly   252 RELMFQSGPNNPWLVKIYKDGAKHYFSTTMAEEIFQTGLVPSYTDFDIFVEYGNLIGLDIGQCIN 316
            |||:||:||.|.||:..|.:.|.|...:.:.:|:||:|:.|..|||.||.::|.:.|||:....|
 Worm   260 RELLFQAGPANQWLLNSYLEAAIHPHCSVIGQEVFQSGVYPGDTDFRIFRDHGRVPGLDLAFVQN 324

  Fly   317 GFVYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSANPTGNTIFFDVLGLYLISYSA 381
            |:.:||::|..:.|.:.:||..|:|:...:..|..:..|...:......|:|||.|||::|.|..
 Worm   325 GYWWHTEFDTAERITKGSLQRAGENVYSTLNHLLKSPYLEKPAEYADRKTVFFDFLGLFVIIYPL 389

  Fly   382 DVGVKLNYAVAAAAIILIYISLLRIAEKSSVSSEQILS-TFILVLVVQ---LIAFVLALALPLLV 442
            .:...:|              :|.|....::.|.:..| |||..|.::   |....:||.|..:.
 Worm   390 SIAHLVN--------------MLTICTVIALMSHRFYSKTFITFLALRDYVLTILTIALVLKAMT 440

  Fly   443 AYGLDKYGLSLSYFATPSLLIGLYICPSL-LGLTLPSYIYLKLANTEKVSFAQQVQLALHGHAAV 506
            ...|..|| :|.::....|.:..|..||: .|:::...:..:||...:..:...::|.   |..:
 Worm   441 FMSLFTYG-ALRWYTRHWLALVAYGLPSVWAGISVQGLLTARLAPKAREEYGSTLELI---HLTL 501

  Fly   507 LSILCIAINYYGLRTTY------------VITWTLAFYVIPLAFNLLTTLHDRGYSWTGILKIVQ 559
            :|.:.:|..||.:.:.:            :||:..|:...| .||.:.||         ||....
 Worm   502 ISGILLAFTYYDIASGFLFALLLVPAIKSIITYFGAWPTCP-TFNTILTL---------ILSFPG 556

  Fly   560 VAPFMYNSYLFYCFIVILTPMMGRFGVDTNPDLIIGALTALGT---ILSMGFLILLVNMSRRSG- 620
            .|..:|.:.:   .:.|..|:|||...  ||:..:....|...   :||:|.|:.....||.|.
 Worm   557 CAMAIYTTEM---LLSIFIPIMGRSSY--NPEPAVSFFVAFSAGCIVLSLGGLVAKSRNSRSSNE 616

  Fly   621 -------FVLIGLLAVTAAGVYIASSTDIGF---PYR-----PKTNVQRVPYLQVRRIFYEYDGT 670
                   :.::|:|.||...:|:.||    |   |||     |  ..:|..:..|.::.|:.:|.
 Worm   617 AGLLELIYNILGVLLVTLTILYVFSS----FWPSPYRFDNVYP--TAKRTQFFHVNQMLYDRNGQ 675

  Fly   671 VSKDESGYLFNLQDRRGL--TPLLESNVDLTGLVNMTSDCAKYMMCGMPLYDHR-WVEAMETTMW 732
            :|.:::.:.....|.||.  .|.::.:.:.|||           .|.   |::. |.|
 Worm   676 ISVNDTRFYAISHDYRGAEDIPFVKKDPEYTGL-----------QCH---YENNPWCE------- 719

  Fly   733 LPRKNPVWTPAEPILKQLNKTVLA-------------------------DGQ-TVQFEFELTTSD 771
                .|...|.:..|.:.|..|.:                         ||: .:::.|.:..:.
 Worm   720 ----TPFLFPTKGRLNERNIRVRSVDERLKFKHPVKILGISKRHGVDSKDGKGNIEYSFSVIGTG 780

  Fly   772 HTSIFISPNEDVIISNWSFLKEYLTTNSPPYH---IYYSFGIDNT--PLRFHIELKKADGVYT-- 829
            ..|::|.|:...:|:|.|     :|....|..   :||:....|.  ...|.:.:||.....:
 Worm   781 QISVYIIPDTTWLITNTS-----VTQPKTPQENMFLYYTCSTPNNICEWMFKVTIKKTTQTPSDD 840

  Fly   830 VPLFQMGIGAHYMH-VKGDDESIR---------LANSLPDYAVSIQ-W--PAMYKKY 873
            .||. :||.:||:| .:...|||:         ..|| |::.|:.. |  ..:||.:
 Worm   841 KPLL-IGISSHYLHGPEMQSESIKNMIAKIQENRVNS-PEWTVTASAWNVDQVYKYF 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:193497	118/315 (37%)
C44B7.11	NP_495410.4	M28_Fxna_like	75..387	CDD:193497	118/314 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	230	1.000	Domainoid score	I1390
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		mtm4849
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780