DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10081 and ermp1

DIOPT Version :9

Sequence 1:	NP_611418.1	Gene:	CG10081 / 37226	FlyBaseID:	FBgn0034441	Length:	875	Species:	Drosophila melanogaster
Sequence 2:	XP_005173917.3	Gene:	ermp1 / 101883637	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	886	Identity:	270/886 - (30%)
Similarity:	428/886 - (48%)	Gaps:	116/886 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 GGIVLFWALLFIAVVKPLFYRLPEPLTVEDASKGGFIAERAQANLYDFEAIGTKVVGSDENEHKT 104
            |.:.|.|.|:.:: |:.|..|.|          |.|.|.||:.:|....::|.:.|||.|||..|
Zfish    63 GFVCLLWTLVHLS-VQQLIIRSP----------GTFNALRARKHLDQITSVGPRTVGSPENEILT 116

  Fly   105 VQFLLKELNLIKDNIQEDLFDMEIDLQYAYGAY---VKWNLVNMYQGIQNVVVKLTPKGTTSENY 166
            |.:||:::..|:...:.....:.:|:|...|::   ......:.|..:.|:.|||.|| ::::::
Zfish   117 VNYLLEQIEQIRSESRSGPHSITVDVQKPTGSFSIDFLGGFTSYYDRVTNIAVKLEPK-SSAQHF 180

  Fly   167 ILVNSHFDSQPTSPSTGDDGHMVVSILEVLRVISSRRKSFEHPIIFLINGSEENSLQASHGFIAY 231
            :|.|.||||...||...||......:||||..:::.....:|.:|||.||:|||.||||||||..
Zfish   181 MLANCHFDSVANSPGASDDAVSCSVMLEVLHSLANLSTPIKHGVIFLFNGAEENILQASHGFITQ 245

  Fly   232 HKWAKNCKAVINLDAAGSGGRELMFQSGPNNPWLVKIYKDGAKHYFSTTMAEEIFQTGLVPSYTD 296
            |.||:..:|.|||:|||.||:|::||:||.|||||:.|...|.|.|::.:.:|:||:|::||.||
Zfish   246 HPWAQQVRAFINLEAAGVGGKEVVFQTGPENPWLVQAYVRAAVHPFASVVGQEVFQSGIIPSDTD 310

  Fly   297 FDIFVEYGNLIGLDIGQCINGFVYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSAN 361
            |.|:.::||:.|:|:....|||:||||||..:.|...::|..|||:|.::|.|..:.||.|.|..
Zfish   311 FRIYRDFGNIPGIDLAFIENGFIYHTKYDTPERIHTDSIQRAGDNILSVLQHLVMSDELADSSVY 375

  Fly   362 PTGNTIFFDVLGLYLISYSADVGVKLNYAVAAAAIILIYIS--------LLRIAEKSSVSSEQIL 418
            ..||.:|||||||.:::|.|.|...:||..|||.  |:|:|        :..:.:.:......:|
Zfish   376 RHGNMVFFDVLGLMVVAYPARVAAIINYLTAAAT--LVYLSRKCSGGAGVRYLRDVACAVCVCVL 438

  Fly   419 STFILVLVVQLIAFVLALALPLLVAYGLDKYGLSLSYFATPSLLIGLYICPSLLGLTLPSYIYL- 482
            |.|:.:|.:.::|.:|.|            .|.|:.::.      ..|....|.|....:.|.|
Zfish   439 SWFVTLLTLLIVALLLTL------------LGRSMFWYT------HFYAAVCLYGSAAAAKIILI 485

  Fly   483 -KLANTEKVSFAQQVQLALHGHAAVLSILCIAINYY---GLRTTYVITWTLAFYVIPLAFNLLTT 543
             .||.....:....|.||.......|.:.|.|:.:.   ||.:.||   .:...|.||...:|..
Zfish   486 HTLAKNLYYTGVSAVDLAELFFDVGLLLWCCALVFLTLNGLCSAYV---PMMMVVFPLLSKVLLR 547

  Fly   544 LHDRG------YSWTGILKIVQVAPFMYNSYLFYCFIVILTPMMGRFGVDTNPDLIIGALTALGT 602
            .|.|.      ||...::.:  ..|:::..:|.:....|.||::||.|.:..||:::.||..|..
Zfish   548 THFRAKGASLQYSVFYLMGL--SVPYVHIMFLIWVVFEIFTPILGRSGTEIPPDVVLAALITLAA 610

  Fly   603 ILSMGFLILLVNMSRRSGFVLIGLLAVTAAGVYIASSTDIGFPY-------RPKTNVQRVPYLQV 660
            ::...:|:.|:.:|..:..:|..|.:|.|. :::.....:.|||       |||    ||.....
Zfish   611 VILSSYLMHLLYLSCSTKRMLAALGSVFAV-MFVLVGCGLFFPYSADPSSPRPK----RVFVQHT 670

  Fly   661 RRIFYEYDGTVSKDESGYLFNLQDRRGL------TPLLESNVDLTGLVNMTSDCAKYM-MCGMPL 718
            .|:|:..||:|.:.:||...|..|..|:      .|.|..::        .:.|...: .||.|
Zfish   671 TRVFHALDGSVERSDSGLWINSLDYTGMQHISAHVPQLNDSI--------RTRCQHTLPYCGFP- 726

  Fly   719 YDHRW---VEAMETTMW-LPRKNPVWTPAEPILKQLNKTVLADGQTVQFEFELTTSDHTSIFISP 779
                |   |:.:....| ||.  |..:|..|:..:|.....::..|::..||.....|.|:::.|
Zfish   727 ----WFLPVKFLVKKSWYLPA--PAVSPEAPLEFRLLSRQQSEWGTLRLSFEAKGPTHMSLYLLP 785

  Fly   780 NEDVIISNWSFLKEYLTTNSP------PYHIYYSFGIDNTPLRFHIELKK--ADGVYTVPLFQMG 836
            .....:..|||     ...:|      .|.|:||.|.|....||.:|::.  :|......|..:.
Zfish   786 VSGASLIGWSF-----GDGTPRFDLSGEYFIFYSHGTDAPAWRFSLEVQPGVSDASPDEGLLALA 845

  Fly   837 IGAHYMHVKGDDESI----RLANSLPDYAVSIQWPAMYKKY 873
            |.|||.  .|.|:..    .|.|:.||:|....|.:.|..|
Zfish   846 ISAHYF--SGPDKHSPPLHTLINTFPDWAFPSAWSSTYHMY 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:193497	129/309 (42%)
ermp1	XP_005173917.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010