DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10073 and TRE1

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_015149.1	Gene:	TRE1 / 855927	SGDID:	S000006097	Length:	783	Species:	Saccharomyces cerevisiae

Alignment Length:	441	Identity:	92/441 - (20%)
Similarity:	152/441 - (34%)	Gaps:	110/441 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AVRSRFDTCKNKISDEPIEDAVRSASSKKIKNQEQYLR-------------GPWYLATGFLLFWA 55
            |:|.|          .|:.|.|     .||:..||..|             |..|.:.|.::..:
Yeast   397 AIRER----------HPVHDIV-----GKIEGSEQAGRAIVIAAPRNSASYGTMYPSFGTVVLLS 446

  Fly    56 L--LFSAVVL-----PL--FYRIP-TGLTIEDASKGVFIAERAQ---SNLYKLAEIGTKVVGSDN 107
            |  |:..:|.     ||  .|.|. .|....:|.....:.:|.:   |.:|.:.::|...:..|:
Yeast   447 LIQLYQEMVYKFDWKPLRNIYFISFGGSEFNEAGATELMEKRTEALKSEIYTIIDVGQIGIWDDS 511

  Fly   108 NENKTVDYLMGLVNEIQENCLDDYFDIEVDLQEVSGSYIHWTMVNMYQGVQNIVIKLSP--KNTT 170
            | |..:.....||:..|:|.....|:::||.....|.   ||.. :.||:...:|. ||  .|..
Yeast   512 N-NLEIQCHPLLVDLFQKNMTSRKFNVKVDNVHQFGD---WTPY-LAQGIPVAIIS-SPGVMNRE 570

  Fly   171 STTYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASH- 234
            ...| .|...||...........|:::..|:  |.::..:.:.|..|.:         |...|:
Yeast   571 HPIY-TVEDKFDFIKDKLRDKKKGEVLSEIM--LYLVEKSLELIDDPFI---------PFSISNY 623

  Fly   235 -GFI--TQHKWAKNCKVVLNLDAAGNGGSDIVFQTGPNSPWLVEKYKE-------NAPHYLATTM 289
             .|:  |.....|.|...:|.|....|.:     ...|:....||:|.       .|..|:..|:
Yeast   624 VDFLSTTLKDLQKECPDTVNFDEVFLGTT-----LWENTKLQFEKWKSEWTELMYGAGTYIEPTI 683

  Fly   290 ----------------AEEIFQTGILPSDTDFAIFVKYGNLIGLDMAKFINGFAYHTKYDQFSNI 338
                            ..:..:.|::  |..|...|.:|..:.:|....:..:.:....|..:..
Yeast   684 IAINRWSWNYLLSLIGVTQCLEEGLM--DRTFYKNVIFGPKLWVDKGDPLRSWTFPEIRDTIAIK 746

  Fly   339 PRGSIQNTGDNLLGLVRSIANSTELDNTEAYATGHAIFFDVLGLYFISYTE 389
            ...|:| ...|.||        |.|.||..|      |.:...|:.|:..|
Yeast   747 DWSSVQ-VQANTLG--------TILQNTARY------FLENKNLHGINTNE 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	68/338 (20%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401
TRE1	NP_015149.1	PA	221..374	CDD:333703
		M28_PMSA_TfR_like	402..617	CDD:349871	52/237 (22%)
		TFR_dimer	642..769	CDD:398094	27/148 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900