Protein Alignment CG10073 and APE3

DIOPT Version :10

• Sequence 1: NP_001261090.1
• Gene: CG10073 / 37225
• FlyBaseID: FBgn0034440
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_009845.2
• Gene: APE3 / 852589
• SGDID: S000000490
• Length: 537
• Species: Saccharomyces cerevisiae
• Alignment Length: 523
• Identity: 93/523 - (17%)
• Similarity: 157/523 - (30%)
• Gaps: 234/523 - (44%)

  Fly    53 FWAL-LFSAVVLPLFYR------------IPTGLTIEDAS---------------KGVFIAERAQ 89
            |:|. |.||.|:|.|::            :|. |..:|:|               |....:|:.|
Yeast    13 FYATNLGSAYVIPQFFQEAFQQEEPIENYLPQ-LNDDDSSAVAANIPKPHIPYFMKPHVESEKLQ 76

  Fly    90 S------------NLYKLAEIG-------TKVVGSDNNENKTVDYLMGLVNEIQENCLDDYFDIE 135
            .            :||:||...       |:|:|| ...|||::|::.:.:::|     ||:|:.
Yeast    77 DKIKVDDLNATAWDLYRLANYSTPDYGHPTRVIGS-KGHNKTMEYILNVFDDMQ-----DYYDVS 135

  Fly   136 V-DLQEVSGSYIHWTMVNMYQG---VQNIVIKLSP------------------------------ 166
            : :.:.:||..|.:.:.:...|   .......|||
Yeast   136 LQEFEALSGKIISFNLSDAETGKSFANTTAFALSPPVDGFVGKLVEIPNLGCEEKDYASVVPPRH 200

  Fly   167 ---------------------------------------------------KNTTSTT------- 173
                                                               |:|.:|.
Yeast   201 NEKQIALIERGKCPFGDKSNLAGKFGFTAVVIYDNEPKSKEGLHGTLGEPTKHTVATVGVPYKVG 265

  Fly   174 ---------------YLLVNS---------------------------HFDSKPTSPSAGDAGQM 196
                           |..::|                           |.||....|...|.|..
Yeast   266 KKLIANIALNIDYSLYFAMDSYVEFIKTQNIIADTKHGDPDNIVALGAHSDSVEEGPGINDDGSG 330

  Fly   197 VVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASHGFITQHKWAKNCKVVLNLD----AAGN 257
            .:::|.|.:.:...|  |.:.|.|....|||..|..|:.:.......:|.|:.:.:|    |:.|
Yeast   331 TISLLNVAKQLTHFK--INNKVRFAWWAAEEEGLLGSNFYAYNLTKEENSKIRVFMDYDMMASPN 393

  Fly   258 GGSDIVFQTGPNSP--------WLVEKYKENAPHYLATTMAEEIFQTGILPSD--TDFAIFVKY- 311
            ...:|.......:|        ..|:.||   .|:|..|         ::|.|  :|:..|:..
Yeast   394 YEYEIYDANNKENPKGSEELKNLYVDYYK---AHHLNYT---------LVPFDGRSDYVGFINNG 446

  Fly   312 ----GNLIGLDMAKFING----FAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANS--TELDNT 366
                |...|.:.....||    ..||...|..||:       :.|..:...:.||:|  |..|:.
Yeast   447 IPAGGIATGAEKNNVNNGKVLDRCYHQLCDDVSNL-------SWDAFITNTKLIAHSVATYADSF 504

  Fly   367 EAY 369
            |.:
Yeast   505 EGF 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:349872	81/468 (17%)
APE3	NP_009845.2	M28_SGAP_like	78..506	CDD:349873	77/454 (17%)
		PA_ScAPY_like	155..284	CDD:239045	8/128 (6%)