DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10073 and AT1G67420

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_001321979.1	Gene:	AT1G67420 / 843062	AraportID:	AT1G67420	Length:	943	Species:	Arabidopsis thaliana

Alignment Length:	902	Identity:	216/902 - (23%)
Similarity:	380/902 - (42%)	Gaps:	205/902 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 WYLA----TGFLLFWALLF-----SAVVLPLFYR-----IPTGLTIEDASKGVFIAERAQSNLYK 94
            |.::    |||...::|:|     ||:|..:.:.     :|....:|..|:.     ||..::..
plant    53 WKMSARDVTGFKFLFSLVFIYALMSAIVYSVLHMKFISPLPANAPLERFSEA-----RAVEHIRV 112

  Fly    95 LAEIGTKVVGSDNNE---NKTVDYLMGLVNEIQENCLDDYFDIEVDLQEVSGSYIHWTMVNM--- 153
            |||   ::.|.....   .:...|:...:..::|.. .....:||:..:|.||:   :|:.:
plant   113 LAE---EIDGRQEGRPGLKEAATYIKSQLEMVKERA-GPNLRVEVEETQVDGSF---SMMFLGHS 170

  Fly   154 ----YQGVQNIVIKLSPKNTTST-TYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMCSTKQA 213
                |:...||::::|..|:..| ..:|:|:|:||...||.|||.|..|.::||:.|::..:...
plant   171 ISLGYRNHTNILMRISSMNSLDTDASVLMNAHYDSPVNSPGAGDCGSCVASLLELARLVVDSGWV 235

  Fly   214 IRHPVVFLLNGAEENPLQASHGFITQHKWAKNCKVVLNLDAAGNGGSDIVFQTGPNSPWLVEKYK 278
            ...||:||.|||||..:..||||:|:||........:|::|:|.||.|:|.|:||.| |....|.
plant   236 PPQPVIFLFNGAEELFMLGSHGFMTKHKLKDTIGAFINVEASGTGGIDLVCQSGPGS-WPSYVYS 299

  Fly   279 ENAPHYLATTMAEEIFQTGILPSDTDFAIFVK-YGNLIGLDMAKFINGFAYHTKYDQFSNIPRGS 342
            :.|.:.:|.:.|:::|.  ::|.|||:.:|.: |.::.|||:...:.|:.|||.:|....|..||
plant   300 QAAVYPMAQSSAQDVFP--VIPGDTDYRMFAEDYADIPGLDIIFLLGGYYYHTTFDTVDRIVPGS 362

  Fly   343 IQNTGDNLLGLVRSIANSTELD----------NTEAYATGHAIFFDVLGLYFISYTESNGVILNY 397
            :|..|:||:.::::.|:|:.|.          :..:.....|:|||.|..:.:.|......:|:.
plant   363 MQARGENLISVLKAFASSSRLKVASERKTLDVDANSDMVERAVFFDYLTWFMVFYPRRVAFVLHN 427

  Fly   398 SVAGVAL-VLIFLSIW--RTSSISRVSIGHVLCWFILIFVLQII----AFVLGLGLPIVVAYVFD 455
            ..|.:.| |..||.:.  ||         |.|..|...|...::    ..:||:.:|::.|.:..
plant   428 IPAALFLCVPFFLYMMDPRT---------HPLLSFFWAFFKGVMHHFAGILLGVIVPVLFAVIRL 483

  Fly   456 KYGLSITYFSTPVLLIGLYICPSLLGLSLPSYI--------------YLKLQRSEKVGF------ 500
            .:...:::|:...|...::|..|..||.:|..|              .:|::.|::..|
plant   484 FFAYPMSWFAHSYLAFLMFIPCSFFGLLIPRAISDRVSHFQGVSSKKIMKVEPSDEARFWGAFGF 548

  Fly   501 -----AQHLQLVLHGH--------AAVLAILDIGLTV--YGLRSAYVPTWTLIFYVIPLAVNLLT 550
                 :.:....|:|.        :.:|..:...|:|  ||..|...|    :||||.|...||.
plant   549 YAFATSAYFFAGLNGGFMTFVISISMLLGWIAFYLSVKSYGYNSIKSP----MFYVIALVPCLLY 609

  Fly   551 TLHDRGFSWTGVLKIFQVVPFLYNSYLIYCFVVTLIPMMGRFGRATNP------DLIISALCALG 609
            :|:     :.|:|.:.                  ||...|..|....|      |:.::|:..:.
plant   610 SLY-----FGGILTLL------------------LIEKTGMMGAIPPPYGFYLADVAVAAVIGIV 651

  Fly   610 TILALGFVIPLVNMFRRPSLILLTLLAISAVTIYTASSTQIGFPY---RPKTNVQRLPYLHV--- 668
            |.|.||.:||:.:.:...|.||..||..:.|.:  |.|:|. |||   .||..|.:..::..
plant   652 TGLCLGPIIPICDRWLAKSSILKFLLHFTVVML--AVSSQF-FPYSKDAPKRVVLQHTFISTGGN 713

  Fly   669 RRIFYEYDGTVV-KNDSGYLFNFQDRRGPAPLKLSKLN---TTGLVSIAADCDTVMMCGFPL--- 726
            ......||..|: .|...::|..      ||....:|:   :..|.:..|......|..||:
plant   714 EITGSSYDLAVIDSNSMEFIFKH------APEVAKELHVGPSFSLGNAEASPQEAWMALFPISCV 772

  Fly   727 --YDHRWVKNRLQIMWLPREEEIITPYEPKLELLSKTELGNNTLRMNFQ---SATTDHASVFI-- 784
              .:.|:......|:....:..::..::|      :|...|.|.|::.:   .....|..:.:
plant   773 LTTNGRFPAKANNILERYSQFPLLQAHKP------QTTFENGTRRVHLELSLGLVGLHKELLLVL 831

  Fly   785 --------QPLEDVII---------SNWSL--------------PTSYI----GQQD 806
                    :.||::.:         |.||.              |.|||    |..|
plant   832 LVINYSICRSLEEIWVTVLNITGPLSGWSFADGKPPAPELPPGGPPSYILRLSGNSD 888

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	97/328 (30%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401	63/287 (22%)
AT1G67420	NP_001321979.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121891
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248924at2759
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm3269
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.780