DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10073 and Naaladl1

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_113947.1	Gene:	Naaladl1 / 83568	RGDID:	620987	Length:	745	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	65/300 - (21%)
Similarity:	110/300 - (36%)	Gaps:	73/300 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 YLLVNSHFDS---KPTSPSAGDAGQMVVAILEVLRVMCS-TKQAI---RHPVVFLLNGAEENPLQ 231
            |::..:|.||   ....||:|.|     .:||:.||:.: .|:..   |..::|...||||..|.
  Rat   367 YVIYGNHRDSWVHGAVDPSSGTA-----VLLEISRVLGTLLKKGTWRPRRSIIFASWGAEEFGLI 426

  Fly   232 ASHGFITQ--HKWAKNCKVVLNLD----------AAGNGG-SDIVFQ-----TGPNSPWL----- 273
            .|..|..:  .|..:.....:|:|          |.|... ..::|.     :.|.|..|
  Rat   427 GSTEFTEEFLSKLQERTVTYINVDISVFSNATLRAQGTPPVQSVIFSATKEISAPGSSGLSIYDN 491

  Fly   274 -VEKYKENAPHY-LATTMAEEIFQTGILPSDTDFAIFVKYGNLIGLDMAKFINGF--------AY 328
             :.....::|.| |..:|       |.|.:.:|:|.|:.:..:..:|:|...:..        .|
  Rat   492 WIRYTNRSSPVYGLVPSM-------GTLGAGSDYASFIHFLGITSMDLAYTYDRSKTSARIYPTY 549

  Fly   329 HTKYDQFSNIPR----------GSIQNTGDNLLGLVRSIANSTELDNTEAYATGHAIFFDV---- 379
            ||.:|.|..:.:          ...:..|..||.|..|:....   |...|:.....|...
  Rat   550 HTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDSLFLPL---NVSDYSETLQSFLQAAQEN 611

  Fly   380 LGLYFISYTESNGVIL----NYSVAGVALVLIFLSIWRTS 415
            ||....|:..|.|.::    .:..|..||....|::.::|
  Rat   612 LGALLESHNISLGPLVTAVEKFKAAAAALNQHILTLQKSS 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	57/266 (21%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401	4/17 (24%)
Naaladl1	NP_113947.1	Zinc_peptidase_like	53..>126	CDD:387401
		PA_GCPII_like	119..331	CDD:239036
		M28_PSMA_like	<353..592	CDD:349942	52/236 (22%)
		TFR_dimer	621..740	CDD:367885	6/30 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900