DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10073 and AT5G20660

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_197566.1	Gene:	AT5G20660 / 832189	AraportID:	AT5G20660	Length:	910	Species:	Arabidopsis thaliana

Alignment Length:	822	Identity:	197/822 - (23%)
Similarity:	362/822 - (44%)	Gaps:	136/822 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 IPTGLTIEDASKGVFIAERAQSNLYKLAEIGTKVVGSDNNENKTVDYLMGLVNEIQENC---LD- 129
            :|..||.:.|.|..|....|..::..|.:.|...|.||...: .::|::..|.:::|..   :|
plant    67 LPKPLTAKQAGKRGFSEIEAIKHVKALTQFGPHPVSSDALVH-ALEYVLAEVEKVKETAHWEVDV 130

  Fly   130 --DYFDIEVDLQEVSGSYIHWTMVNMYQGVQNIVIKLSPK--NTTSTTYLLVNSHFDSKPTSPSA 190
              |:|:.:..:..:.|.......: :|..:.:||:::.||  :......:||:||.|:..|:..|
plant   131 NVDFFESKFGVNRLVGGLFKGKSL-VYSDISHIVLRILPKYESDAGDNAILVSSHIDTVFTTGGA 194

  Fly   191 GDAGQMVVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASHGFITQHKWAKNCKVVLNLDAA 255
            ||....|..:||:.|....:....::.::||.|..||..|..:|.|||||.|:...::.::|:|.
plant   195 GDCSSCVAVMLELARSASQSAHGFKNSIIFLFNTGEEEGLNGAHSFITQHPWSSTVRLAIDLEAM 259

  Fly   256 GNGGSDIVFQTGPNSPWLVEKYKENAPHYLATTMAEEIFQTGILPSDTDFAIFVKYGNLIGLDMA 320
            |.||...:||.|| |||.:|.:...|.:.....:.:::|.:||:.|.|||.::.:...|.|||.|
plant   260 GTGGKSSIFQAGP-SPWAIENFALAAKYPSGQIIGQDLFTSGIIKSATDFQVYKEVAGLSGLDFA 323

  Fly   321 KFINGFAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANSTEL--DNT----EAYATGHAIFFDV 379
            ...|...||||.|:...|..||:|:.|:|:|..:..:|:|::|  |.|    |......|::|||
plant   324 FADNTAVYHTKNDKIELIKPGSLQHLGENMLAFLLRVASSSDLPKDKTLQGEERSNPDSAVYFDV 388

  Fly   380 LGLYFISYTESNGVILNYSVAGVALVLIFLSIWRTSSISRVSIGHVLCWFILIFVLQIIAFVLGL 444
            ||.|.|.|.:|...:|..||...::::..||::.....:.||:       ||..:..|::::..:
plant   389 LGKYMIVYRQSLATMLYVSVIMQSILIWVLSVFMGGYPAVVSL-------ILSCLSIILSWIFSV 446

  Fly   445 GLPIVVAYVFDKYGLS-ITYFSTPVLLIGLYICPSLLGLSLP----SYIYLKL----QRSEKVGF 500
            ...:.||::......| :.:.|.|.:::||::.|::|| |:.    ::|:|:.    :.|.|:..
plant   447 AFSVAVAFILPWISSSPVPFASNPWMVVGLFVSPAILG-SISGQHVAFIFLRKKSSNRNSNKMQV 510

  Fly   501 AQHLQ-----------LVLHGHAAVLAILDIGLTVYGLRSAYVP-TW-------------TLIFY 540
            :..|:           |...|....|.:|.:| |.|.|.|.|:. .|             ||...
plant   511 SPRLRDNLARLEAERWLFKSGFIQWLVLLALG-TYYKLGSTYLALVWLVPPAFAYGLLEATLSPI 574

  Fly   541 VIPLAVNLLTTLHDRGFSWTGVLKIFQVVPFLYNSYLIYCFVVTLIPMMGRF--GRATNPDLIIS 603
            .:|..:.|.|.|            |...||.|.:|........|:|.|:.||  .....|:.:.|
plant   575 RLPKPLKLATLL------------ISLAVPILVSSGSFIQLTGTMIGMLIRFDSNPGVTPEWLGS 627

  Fly   604 AL--CALGTILALG--FVIPLVNMFRRPSLILLTLLAISAVTIYTASSTQIGFPYRPKTNVQRLP 664
            ||  .|:.|.::|.  :::..:::......|:..|..|:|:::...||..:  |...:...:.:.
plant   628 ALIAVAIATFISLSMVYLLAYIHLSGAKKSIVTALCIITALSLALVSSGVL--PAFTEDTARAVN 690

  Fly   665 YLHVRRIFYEYDG-------TVVKNDSGYLFNFQDRRGPAPLKLSKLNTTGLVSIAADCDTVMMC 722
            .:||    .:..|       ::..|..|.| |.:..:.....:..:.|....||..|..:.|
plant   691 VVHV----VDTSGQDQVAFISLFSNTPGNL-NMEAEQIKEGFRCGRENKIDFVSFEAKYNCV--- 747

  Fly   723 GFPLYDHRWVKNRLQIMWLPREEEIITPYEPKLELLS-KTELGNNTLRMNFQSATTDHASVFIQP 786
                     .|...::.|  .:.:|     |.|.::: |...|...:.::..:..:
plant   748 ---------TKKDAEVGW--DKHDI-----PVLRVINDKEREGGRVIAVSMDTGGS--------- 787

  Fly   787 LEDVIISNWSLP---------TSYIGQQDTSHMYFSYGKNNT 819
                  |.|:|.         |..:|:::...:....|:.::
plant   788 ------SRWTLRIDMDEIEDFTMQVGEEEEEELMIERGEKSS 823

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	99/320 (31%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401	61/279 (22%)
AT5G20660	NP_197566.1	M28_Fxna_like	78..396	CDD:193497	99/320 (31%)
AT5G20660	NP_197566.1	MFS	510..>594	CDD:304372	21/96 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I1221
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248924at2759
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm3522
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830