Protein Alignment CG10073 and ERMP1

DIOPT Version :10

• Sequence 1: NP_001261090.1
• Gene: CG10073 / 37225
• FlyBaseID: FBgn0034440
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Alignment Length: 911
• Identity: 280/911 - (30%)
• Similarity: 443/911 - (48%)
• Gaps: 156/911 - (17%)

  Fly    47 ATGFLLFWALLFSAVVLPLFYRIPTGLTIEDASKGVFIAERAQSNLYKLAEIGTKVVGSDNNENK 111
            |.|..|:...|.:.|.|.|...:..|..   ..:|.|.|.:|:..|..:..||.:..||..||..
Human    74 ALGLALYLIALRTLVQLSLQQLVLRGAA---GHRGEFDALQARDYLEHITSIGPRTTGSPENEIL 135

  Fly   112 TVDYLMGLVN--EIQENCLDDYFDIEVDLQEVSGSY-IHWT--MVNMYQGVQNIVIKLSPKNTTS 171
            ||.||:..:.  |:|.|.|   ..|.||:|..:||: |.:.  ..:.|..:.|:|:||.|::...
Human   136 TVHYLLEQIKLIEVQSNSL---HKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQ 197

  Fly   172 TTYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASHGF 236
            .. :|.|.||||...||.|.|.......:||||||:.::.:|:.|.|:||.||||||.|||||||
Human   198 HA-VLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGF 261

  Fly   237 ITQHKWAKNCKVVLNLDAAGNGGSDIVFQTGPNSPWLVEKYKENAPHYLATTMAEEIFQTGILPS 301
            ||||.||...:..:||:|||.||.::||||||.:||||:.|...|.|..|:.:|:|:||:||:||
Human   262 ITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPS 326

  Fly   302 DTDFAIFVKYGNLIGLDMAKFINGFAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANSTELDNT 366
            ||||.|:..:||:.|:|:|...||:.||||||....|...|||..|||:|.:::.:|.|..|...
Human   327 DTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAA 391

  Fly   367 EAYATGHAIFFDVLGLYFISYTESNGVILNYSVA-GVALVL--IFLS-IWRTSSISRVSIGHVLC 427
            ..|..|:.:|||||||:.|:|....|.|:||.|. ||.|.|  .||. ..:|.:..:
Human   392 SKYRHGNMVFFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKK-------- 448

  Fly   428 WFILIFVLQIIAFVLGLGLPIVVAYVFDKYGLSITYFST--PVLLIGLYICPSLLGLSLPSYIYL 490
                       .|:.|||:.:            |::|::  .||:|.::|  ||:|.||..|.:.
Human   449 -----------DFLCGLGITL------------ISWFTSLVTVLIIAVFI--SLIGQSLSWYNHF 488

  Fly   491 KLQRSEKVGFAQHLQLVLHGHAAVLAIL------------------------DIGLTVY------ 525
                        ::.:.|:|.|.|..|:                        ||.|.|:
Human   489 ------------YVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHCCFLVT 541

  Fly   526 ----GLRSAYVPTWTLIFYVIPLAVNLLTTLHDRGFSWTG---------VLKIFQVVPFLYNSYL 577
                ||.||::   :.::...||...|  .:| :.|...|         :|.:|  :|:||..||
Human   542 LTYQGLCSAFI---SAVWVAFPLLTKL--CVH-KDFKQHGAQGKFIAFYLLGMF--IPYLYALYL 598

  Fly   578 IYCFVVTLIPMMGRFGRATNPDLIISALCALGTILALGFVIPLVNMFRRPSLILLTLLAISAVTI 642
            |:.......|::||.|....||::::::.|..|::...:.|..:.:.:.....:|||..:.|:|.
Human   599 IWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKTMLTLTLVCAITF 663

  Fly   643 YTASSTQIGFPY-----RPKTNVQRLPYLHVRRIFYEYDGTVVKNDSGYLFNFQDRRGPAPL--K 700
            ....|... |||     .||.  :|:...|:.|.|::.:|..||.|||...|..|..|.:.:  .
Human   664 LLVCSGTF-FPYSSNPANPKP--KRVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHITPH 725

  Fly   701 LSKLNTTGLVSIAADC-DTVMMCGFPLY--DHRWVKNRLQIMWLPREEEIITPYE-PKLELLSKT 761
            :.::|.    ||.|.| :...:||||.|  .|..::..   .:||..|  ::|.. |...|:||.
Human   726 IPEIND----SIRAHCEENAPLCGFPWYLPVHFLIRKN---WYLPAPE--VSPRNPPHFRLISKE 781

  Fly   762 ELGNNTLRMNFQSATTDHASVFIQPLEDVIISNWSLPTSYIGQQDTS-----HMYFSYGKNNTAL 821
            :...:::::.|::....|.|.:::..:...:|.|||..   |...||     .:::|:|...:|.
Human   782 QTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGN---GTPVTSKGGDYFVFYSHGLQASAW 843

  Fly   822 TFFIDFYKLDADFAVPLCQIGLAVHFIGNKG------DAISQEFAKKIPSFAAAVDWPASYQRYI 880
            .|:|: .::..:....:..:.:|.|::..:.      ||:.::|    |.:.....|..:|..::
Human   844 QFWIE-VQVSEEHPEGMVTVAIAAHYLSGEDKRSPQLDALKEKF----PDWTFPSAWVCTYDLFV 903

  Fly   881 F 881
            |
Human   904 F 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:349872	140/311 (45%)
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	140/311 (45%)