Protein Alignment CG10073 and Tfr2

DIOPT Version :10

• Sequence 1: NP_001261090.1
• Gene: CG10073 / 37225
• FlyBaseID: FBgn0034440
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_056614.3
• Gene: Tfr2 / 50765
• MGIID: 1354956
• Length: 798
• Species: Mus musculus
• Alignment Length: 270
• Identity: 54/270 - (20%)
• Similarity: 93/270 - (34%)
• Gaps: 91/270 - (33%)

  Fly   175 LLVNSHFDSKPTS--------------------------PSAGDAGQMVVAILEVLRV---MCST 210
            |:||:|..|.|.|                          |.|..:......:||::|.   |.|.
Mouse   394 LVVNNHRVSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSN 458

  Fly   211 KQAIRHPVVFL-LNGAEENPLQASHGFITQHKWAKNCKVVLNLDAA----------GNGGSDIVF 264
            ....|..::|: .:|.:       .|.:...:|.:....||:|.|.          |:|  ....
Mouse   459 GFRPRRSLLFISWDGGD-------FGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDG--KFHA 514

  Fly   265 QTGPNSPWLVEKY--KENAPHYLATTMAEEIFQT---------GILPSDTDFAIFVKYGNLIGLD 318
            :|.|....|:|..  :.::|::...|:.|::..|         ..||.|:....|..:..:..::
Mouse   515 KTSPLLVSLIENILKQVDSPNHSGQTLYEQVALTHPSWDAEVIQPLPMDSSAYSFTAFAGVPAVE 579

  Fly   319 MAKFINGFAY---HTKYDQFSNIP---RGS----------------IQNTGDNLLGL-------- 353
            .:...:...|   |||.|.:.|:.   ||.                |:.:.|:||.|
Mouse   580 FSFMEDDRVYPFLHTKEDTYENLHKMLRGRLPAVVQAVAQLAGQLLIRLSHDHLLPLDFGRYGDV 644

  Fly   354 -VRSIANSTE 362
             :|.|.|..|
Mouse   645 VLRHIGNLNE 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:349872	54/270 (20%)
Tfr2	NP_056614.3	Endocytosis signal. /evidence=ECO:0000255	23..26
		PA_TfR	206..396	CDD:239043	1/1 (100%)
		M28_TfR	404..637	CDD:349946	44/241 (18%)
		TFR_dimer	664..788	CDD:461238