DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10073 and naalad2

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_956571.1	Gene:	naalad2 / 393247	ZFINID:	ZDB-GENE-040426-1025	Length:	745	Species:	Danio rerio

Alignment Length:	301	Identity:	65/301 - (21%)
Similarity:	99/301 - (32%)	Gaps:	95/301 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   599 DLIISALCALGTILA---LGFVIPLVNMFRRPSLILLTLLAISAVTIYTASSTQIGFPYRPKTNV 660
            |.||..:|.|..|.|   :||:|   ..|.|||.:                            |.
Zfish     5 DKIIRWICRLTAITAFFLIGFII---GWFARPSSV----------------------------NH 38

  Fly   661 QRLPYLHVRRIFYEYDGTVVKNDSGYLFNFQDRRGPAPLKLSKLNTTGLVSIAADCDTVMMCGFP 725
            :|                   ....:|.:|.|......:|......|.|..:|.....:.:.
Zfish    39 ER-------------------TSKSFLRDFMDEMHAENIKHHLRKFTKLPHLAGTQQNLNLA--- 81

  Fly   726 LYDHRWVKNRLQIMWLPREEEIITPYEPKLELLSKT---------ELGNNTLRMNFQSATTDHAS 781
                ..::|......|...|  :.||:..|...:||         :|||...:       |..|.
Zfish    82 ----EQIRNEWMEFGLDSVE--LVPYDVLLSYPNKTNPNYISIVDQLGNEIFK-------TSLAE 133

  Fly   782 VFIQPLEDV--IISNWSLPTSYIGQQDTSHMYFSYGKNNTALTFFIDFYKLDADFAVPLC--QIG 842
            ...:..|||  |:..:| ..|..||.:...:|.:||:..       ||:||:.:..:. |  :|.
Zfish   134 PVPEGYEDVADIVPPYS-AFSAKGQPEDELVYVNYGRTE-------DFFKLERELGIN-CTGKIL 189

  Fly   843 LAVH---FIGNKGDAISQEFAKKIPSFAAAVD-WPASYQRY 879
            :|.:   |.|||........||.|..|:...| |....:.|
Zfish   190 IARYGKIFRGNKVKNAVLAGAKGIILFSDPADYWAEDVEPY 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401	14/41 (34%)
naalad2	NP_956571.1	Zinc_peptidase_like	47..>102	CDD:301362	10/63 (16%)
		PA_GCPII_like	108..333	CDD:239036	36/139 (26%)
		M28_PSMA_like	341..581	CDD:193568
		TFR_dimer	618..733	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900