DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10073 and Naalad2

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_001100272.1	Gene:	Naalad2 / 300384	RGDID:	1305872	Length:	778	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	65/313 - (20%)
Similarity:	107/313 - (34%)	Gaps:	102/313 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 IHWTMVNMYQGVQNIVIKLSPKNTTSTTYLLVNSHFDS---KPTSPSAGDAGQMVVAILEVLRVM 207
            :|...:|....:.|::..:. .:|....|:::..|.||   ....|:.|.|     .:.|:.|
  Rat   372 MHVHNINKITRIYNVIGTIR-GSTEPDRYVILGGHRDSWVFGGIDPTTGTA-----VLQEIAR-- 428

  Fly   208 CSTKQAI------RHPVVFLLNGAEENPLQASHGFITQHKWA-KNCKVV-------LNLDAAGNG 258
             |..:.:      |..::|....|||      .|.:...:|| :|.|::       :|.|:|..|
  Rat   429 -SFGKLVNGGWKPRRTIIFASWDAEE------FGLLGSTEWAEENAKILQERSIAYINSDSAIEG 486

  Fly   259 G-----------SDIVFQT---------GPNSPWLVEKYKENAPHYLATTMAEEIFQTGILPSDT 303
            .           ..:|::.         |..|..|.|.:.|..|    :...:|..:...|.|.:
  Rat   487 NYTLRVDCTPLLHQLVYKVAREISSPDDGFESKSLYESWLEKDP----SPENKERPRINKLGSGS 547

  Fly   304 DF-AIFVKYGNLIG-------LDMAKFINGFAYHTKYDQFSNIPRGSIQNTGD----------NL 350
            || |.|.:.|...|       ....|:.:...|||.|:.|.     .:||..|          .|
  Rat   548 DFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFE-----LVQNFYDPTFKKQLSVAQL 607

  Fly   351 LG-LVRSIANSTELD-NTEAYATG---------------------HAIFFDVL 380
            .| ||..:|:...:. |.:.||..                     |.:.||.|
  Rat   608 RGALVYELADCVVIPFNIQDYAKALKNYAASIFNLSKKHDQQLRDHGVSFDPL 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	65/313 (21%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401
Naalad2	NP_001100272.1	Zinc_peptidase_like	86..>143	CDD:417508
		PA_GCPII_like	148..374	CDD:239036	0/1 (0%)
		M28_PSMA_like	<382..623	CDD:349942	56/264 (21%)
		TFR_dimer	655..774	CDD:398094	3/6 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900