Protein Alignment CG10073 and NAALADL2

DIOPT Version :10

• Sequence 1: NP_001261090.1
• Gene: CG10073 / 37225
• FlyBaseID: FBgn0034440
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_011510914.1
• Gene: NAALADL2 / 254827
• HGNCID: 23219
• Length: 805
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 65/341 - (19%)
• Similarity: 121/341 - (35%)
• Gaps: 76/341 - (22%)

  Fly    87 RAQSNLYKL------AEIGTKVVGSD--NNENKTVDYLMGLVNEIQENCLDDYFDIEVDLQEVSG 143
            :::|||..|      |.:..|::.|.  ..:|:....|....|||:.        :.:.:|.|
Human   379 QSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRV--------VSMQVQTV-- 433

  Fly   144 SYIHWTMVNMYQGVQNIVIKLSPKNTTSTTYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMC 208
                 |.:.....|...|:.|    |:...|::|.||..:..:......|....:....:..:|.
Human   434 -----TKLKTVTNVVGFVMGL----TSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMS 489

  Fly   209 STKQAIR--HPVVFLLNGAEENPLQASHGFITQHKWAKNCKVVL--------NLDAAGNGGSDIV 263
            ..|:..|  ..:||...|.      .:.|.|..::|.::.|.||        :|.:...|.|.:.
Human   490 KVKRGWRPDRTIVFCSWGG------TAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLY 548

  Fly   264 FQTGPNSPWL-VEKYKENAPHYLATTMAEEIFQTGI----LPSDTDFAIFVKYGNLIGLDMAKFI 323
            ....|:...| |||...|.      |...:..:|.|    :..|.|:.|     |.:|:.:.:|
Human   549 PVASPSLQQLVVEKNNFNC------TRRAQCPETNISSIQIQGDADYFI-----NHLGVPIVQF- 601

  Fly   324 NGFAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANSTELDNTEAYATGHAIFFDVLGLYFISYT 388
                   .|:....:       .|.:.|...|....:|:::..:.....|.....:.|...:..
Human   602 -------AYEDIKTL-------EGPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQI- 651

  Fly   389 ESNGVILNYSVAGVAL 404
             :|..:|.::...:||
Human   652 -ANEPVLPFNALDIAL 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:349872	61/322 (19%)
NAALADL2	XP_011510914.1	PA	268..420	CDD:333703	9/40 (23%)
		M28_PMSA_TfR_like	437..658	CDD:349871	47/258 (18%)
		TFR_dimer	678..791	CDD:461238