Protein Alignment CG10073 and C44B7.11

DIOPT Version :10

• Sequence 1: NP_001261090.1
• Gene: CG10073 / 37225
• FlyBaseID: FBgn0034440
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_495410.4
• Gene: C44B7.11 / 183431
• WormBaseID: WBGene00016631
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 927
• Identity: 239/927 - (25%)
• Similarity: 418/927 - (45%)
• Gaps: 114/927 - (12%)

  Fly     6 RSRFDTCKNKISDEPIEDAVRSASSKKIKNQEQYLRGPWYLATGFLLFWALLFSAVVLPLFYRIP 70
            |...|..||.:..|.:::   ..:.::::.....||...:...| |.|..|:.....|......|
 Worm     7 RRHADEKKNILEKESLQN---DETQREMEKDISLLRPAHWNFIG-LFFLVLIIGTTFLHKCLPEP 67

  Fly    71 TGLTIEDASKGVFIAERAQSNLYKLAEIGTKVVGSDNNENKTVDYLMGLVNEIQ---ENCLDDYF 132
            .....|:..   |..:||...|.:|::.|.|..||.|.|..|.:.::..:|:|:   :|..:..|
 Worm    68 KDPNQEETQ---FSEKRAVKVLQELSDYGWKPAGSYNCEELTRNRILKELNDIRSQNQNVENLRF 129

  Fly   133 DIEVDLQEVSGSY---IHWT--MVNMYQGVQNIVIKLSPKNTTSTTYLLVNSHFDSKPTSPSAGD 192
            ||  |.|.|||.:   .|.|  |...|:.|.|::.:|..........:|:|.|:||.|||.:..|
 Worm   130 DI--DTQYVSGCFDIPAHDTEGMNICYRNVSNVMARLGKGEKKDKISVLLNCHYDSWPTSNAGSD 192

  Fly   193 AGQMVVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASHGFITQHKWAKNCKVVLNLDAAGN 257
            .......:||::|:.......:.|.|:||.|||||:.|.|:|||||||.|....:..:||:|:|:
 Worm   193 DLSSCALMLELIRLYSKNPHLLNHDVIFLFNGAEESSLLAAHGFITQHSWRHEIRAFINLEASGS 257

  Fly   258 GGSDIVFQTGPNSPWLVEKYKENAPHYLATTMAEEIFQTGILPSDTDFAIFVKYGNLIGLDMAKF 322
            ||.:::||.||.:.||:..|.|.|.|...:.:.:|:||:|:.|.||||.||..:|.:.|||:|..
 Worm   258 GGRELLFQAGPANQWLLNSYLEAAIHPHCSVIGQEVFQSGVYPGDTDFRIFRDHGRVPGLDLAFV 322

  Fly   323 INGFAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANSTELDNTEAYATGHAIFFDVLGLYFISY 387
            .||:.:||::|....|.:||:|..|:|:...:..:..|..|:....||....:|||.|||:.|.|
 Worm   323 QNGYWWHTEFDTAERITKGSLQRAGENVYSTLNHLLKSPYLEKPAEYADRKTVFFDFLGLFVIIY 387

  Fly   388 TESNGVILNYSVAGVALVLIFLSIWRTSSISRVSI-GHVLCWFILIFVLQIIAFVLGLGLPIVVA 451
            ..|...::|.......:.|:....:..:.|:.::: .:||....:..||:.:.|:
 Worm   388 PLSIAHLVNMLTICTVIALMSHRFYSKTFITFLALRDYVLTILTIALVLKAMTFM---------- 442

  Fly   452 YVFDKYGLSITYFSTPVLLIGLYICPSL-LGLSLPSYIYLKLQRSEKVGFAQHLQLVLHGHAAVL 515
            .:| .|| ::.:::...|.:..|..||: .|:|:...:..:|....:..:...|:|:   |..::
 Worm   443 SLF-TYG-ALRWYTRHWLALVAYGLPSVWAGISVQGLLTARLAPKAREEYGSTLELI---HLTLI 502

  Fly   516 AILDIGLTVYGLRSAYVPTWTLIFYVIPLAVNLLTTLHDRGFSWTGVLKIFQVVPFLYNSY---- 576
            :.:.:..|.|.:.|.::    ....::|...:::|...    :|. ....|..:..|..|:
 Worm   503 SGILLAFTYYDIASGFL----FALLLVPAIKSIITYFG----AWP-TCPTFNTILTLILSFPGCA 558

  Fly   577 -LIYCFVVTL---IPMMGRFGRATNPDLIISALCALGT---ILALGFVIPLVNMFRRPS------ 628
             .||...:.|   ||:|||  .:.||:..:|...|...   :|:||.::......|..:
 Worm   559 MAIYTTEMLLSIFIPIMGR--SSYNPEPAVSFFVAFSAGCIVLSLGGLVAKSRNSRSSNEAGLLE 621

  Fly   629 LI--LLTLLAISAVTIYTASSTQIGF---PYR-----PKTNVQRLPYLHVRRIFYEYDGTVVKND 683
            ||  :|.:|.::...:|..||    |   |||     |  ..:|..:.||.::.|:.:|.:..||
 Worm   622 LIYNILGVLLVTLTILYVFSS----FWPSPYRFDNVYP--TAKRTQFFHVNQMLYDRNGQISVND 680

  Fly   684 SGYLFNFQDRRGPAPLKLSKLNT--TGLVSIAAD---CDTVMMCGFPLYDHRWVKNRL---QIMW 740
            :.:.....|.||...:...|.:.  |||.....:   |:|..:  ||      .|.||   .|..
 Worm   681 TRFYAISHDYRGAEDIPFVKKDPEYTGLQCHYENNPWCETPFL--FP------TKGRLNERNIRV 737

  Fly   741 LPREEEIITPYEPKLELLSK-----TELGNNTLRMNFQSATTDHASVFIQPLEDVIISNWSLPTS 800
            ...:|.:...:..|:..:||     ::.|...:..:|....|...||:|.|....:|:|.|: |.
 Worm   738 RSVDERLKFKHPVKILGISKRHGVDSKDGKGNIEYSFSVIGTGQISVYIIPDTTWLITNTSV-TQ 801

  Fly   801 YIGQQDTSHMYFSYGKNNTALTFFIDFYKLDADFAV-------PLCQIGLAVHFIGN---KGDAI 855
            ....|:...:|::....|....:   .:|:......       ||. ||::.|::..   :.::|
 Worm   802 PKTPQENMFLYYTCSTPNNICEW---MFKVTIKKTTQTPSDDKPLL-IGISSHYLHGPEMQSESI 862

  Fly   856 SQEFAKKIPSFAAAVDW 872
            ....||...:...:.:|
 Worm   863 KNMIAKIQENRVNSPEW 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:349872	115/314 (37%)
C44B7.11	NP_495410.4	M28_Fxna_like	75..387	CDD:349872	115/316 (36%)
		COG5373	<444..>646	CDD:444140	46/221 (21%)